STRINGSTRING
bapC bapC bapB bapB BPSS1528 BPSS1528 bsaR bsaR bipD bipD bsaO bsaO bsaZ bsaZ pilN pilN bipB bipB bsaS bsaS bsaV bsaV
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bapCSimilar to Salmonella typhi invasion protein IagB or sty3000 SWALL:IAGB_SALTI (SWALL:P43018) (160 aa) fasta scores: E(): 2e-11, 42.27% id in 123 aa, and to Burkholderia pseudomallei hypothetical 18.2 kDa protein SWALL:Q9ZF87 (EMBL:AF110185) (161 aa) fasta scores: E(): 5.2e-21, 47.68% id in 151 aa. (187 aa)    
Predicted Functional Partners:
bapB
Acyl carrier protein; Similar to Saccharopolyspora erythraea acyl carrier protein AcpP SWALL:ACP_SACER (SWALL:P11830) (95 aa) fasta scores: E(): 0.0043, 36.84% id in 76 aa, and to Thermotoga maritima acyl carrier protein AcpP or tm0662 SWALL:Q9WZD0 (EMBL:AE001739) (81 aa) fasta scores: E(): 9.7e-05, 31.88% id in 69 aa.
  
  
 0.890
BPSS1528
Hypothetical protein; No significant database matches.
       0.773
bsaR
Similar to Salmonella typhimurium, and Salmonella typhi surface presentation of antigens protein SpaK or InvB or stm2895 or sty3018 SWALL:SPAK_SALTY (SWALL:P39443) (135 aa) fasta scores: E(): 4e-06, 27.61% id in 134 aa, and to Shigella sonnei surface presentation of antigens protein spak spak or spa15 SWALL:SPAK_SHISO (SWALL:Q55296) (133 aa) fasta scores: E(): 1.9e-05, 26.51% id in 132 aa.
  
  
 0.761
bipD
Putative membrane antigen; Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and their final integration into the target cell membrane; Belongs to the invasin protein D family.
  
  
 0.758
bsaO
Type III secretion system protein; Similar to Salmonella typhimurium InvG protein precursor InvG or stm2898 SWALL:INVG_SALTY (SWALL:P35672) (562 aa) fasta scores: E(): 1.8e-22, 44.5% id in 519 aa, and to Escherichia coli O157:H7 type III secretion apparatus protein z4197 or ecs3733 SWALL:Q8X6D6 (EMBL:AE005515) (567 aa) fasta scores: E(): 4e-36, 40.81% id in 517 aa.
 
  
 0.665
bsaZ
Surface presentation of antigens protein; Part of the bsa type III secretion system, is involved in the intracellular replication of invading bacteria inside the host cell. Probably necessary for the lysis of the vacuole membrane and escape into the host cell cytoplasm.
 
  
 0.571
pilN
Putative type IV pilus biosynthesis protein; Similar to Escherichia coli PilN protein SWALL:Q9F533 (EMBL:AP002527) (547 aa) fasta scores: E(): 2.3e-27, 32.99% id in 588 aa, and to Yersinia pseudotuberculosis lipoprotein PilN SWALL:Q8KR30 (EMBL:AY047316) (530 aa) fasta scores: E(): 5.2e-27, 35.94% id in 409 aa.
 
    0.550
bipB
Putative cell invasion protein; Plays a role in the bacterium-induced formation of multinucleated giant cell (MNGC), which is formed after host cell fusion, as well as in the intercellular spreading of bacteria and in the induction of apoptosis in macrophages. May act in concert with other effector proteins to induce fusion of host cell membranes.
     
 0.542
bsaS
Surface presentation of antigens protein; Similar to Salmonella typhimurium, and Salmonella typhi probable ATP synthase SpaL or InvC or stm2894 or sty3017 SWALL:SPAL_SALTY (SWALL:P39444) (431 aa) fasta scores: E(): 9.6e-86, 59.15% id in 426 aa, and to Escherichia coli O157:H7 type III secretion apparatus protein z4194 or ecs3730 SWALL:Q8X6E2 (EMBL:AE005515) (439 aa) fasta scores: E(): 1.5e-83, 56.14% id in 431 aa.
 
  
 0.536
bsaV
Surface presentation of antigens protein; Similar to Salmonella typhimurium SpaO SWALL:Q57524 (EMBL:U29358) (303 aa) fasta scores: E(): 0.045, 28.34% id in 314 aa.
 
  
 0.521
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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