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BPSS1689 BPSS1689 gca gca BPSS1834 BPSS1834 BPSL0618 BPSL0618 wcbK wcbK BPSS0422 BPSS0422 BPSS1687 BPSS1687 BPSS1835 BPSS1835 wcbE wcbE BPSS1830 BPSS1830 wbiB wbiB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
BPSS1689Similar to Xylella fastidiosa UDP-glucose 4-epimerase xf0610 SWALL:Q9PFP7 (EMBL:AE003906) (295 aa) fasta scores: E(): 9.9e-53, 53.71% id in 296 aa, and to Xanthomonas campestris UDP-glucose 4-epimerase Rmd or xcc0608 SWALL:AAM39924 (EMBL:AE012159) (312 aa) fasta scores: E(): 1.3e-49, 50.65% id in 304 aa. (322 aa)    
Predicted Functional Partners:
gca
GCP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
 
  
 
0.982
BPSS1834
Putative lipopolysaccharide biosynthesis related protein; Similar to Escherichia coli putative colanic biosynthesis UDP-glucose lipid carrier transferase WcaJ or b2047 SWALL:WCAJ_ECOLI (SWALL:P71241) (464 aa) fasta scores: E(): 2.5e-59, 39.65% id in 469 aa, and to Salmonella typhimurium putative undecaprenylphosphate glucosephosphotransferase WcaJ or stm2103 SWALL:Q9F799 (EMBL:AF285085) (464 aa) fasta scores: E(): 2.8e-58, 38.92% id in 465 aa. Note: Also similar to BPSL0618 (473 aa) fasta scores: E(): 3.5e-96, 50.433% identity in 462 aa overlap.
 
  
 0.931
BPSL0618
Putative sugar transferase; Similar to Escherichia coli putative colanic biosynthesis UDP-glucose lipid carrier transferase WcaJ SWALL:WCAJ_ECOLI (SWALL:P71241) (464 aa) fasta scores: E(): 9.8e-58, 37.08% id in 480 aa, and to Klebsiella pneumoniae probable capsular polysaccharide biosynthesis glycosyltransferase SWALL:YC14_KLEPN (SWALL:Q48460) (465 aa) fasta scores: E(): 8.3e-54, 35.71% id in 476 aa. Similar to BPSS1834, 50.433% identity (50.873% ungapped) in 462 aa overlap.
 
  
 0.930
wcbK
Putative GDP sugar epimerase/dehydratase protein; Similar to Aneurinibacillus thermoaerophilus GDP-6-deoxy-D-lyxo-4-hexulose reductase Rmd SWALL:Q9EYP5 (EMBL:AF317224) (309 aa) fasta scores: E(): 4.3e-31, 35.4% id in 322 aa. Identical to Burkholderia mallei putative GDP epimerase/dehydratase WcbK SWALL:Q9AI38 (EMBL:AF285636) (337 aa) fasta scores: E(): 1.2e-132, 100% id in 337 aa.
  
  
 
0.924
BPSS0422
Putative aminotransferase; C-terminal region similar to Escherichia coli, and Escherichia coli O157:H7 perosamine synthetase Per or RfbE or z3200 or ecs2841 SWALL:O07849 (EMBL:AF061251) (366 aa) fasta scores: E(): 3.5e-50, 38.76% id in 356 aa and N-terminal region similar to Agrobacterium tumefaciens acetyltransferase atu2080 or agr_c_3768 SWALL:Q8UDP1 (EMBL:Q8UDP1) (177 aa) blastp scores: Score = 39.9 bits (91), Expect = 0.14 Identities = 46/165 (27%), Positives = 70/165 (41%), Gaps = 18/165 (10%); Belongs to the DegT/DnrJ/EryC1 family.
    
 0.908
BPSS1687
Putative membrane protein; Similar to Rhizobium loti hypothetical protein mlr1941 SWALL:Q98JH3 (EMBL:AP002998) (388 aa) fasta scores: E(): 3.8e-18, 35.77% id in 355 aa, and to Corynebacterium glutamicum predicted acyltransferases cgl2858 SWALL:BAC00251 (EMBL:AP005283) (356 aa) fasta scores: E(): 1.2e-11, 29.73% id in 380 aa.
     
 0.669
BPSS1835
Putative LPS biosynthesis mannose-1-phosphate guanylyltransferase; Similar to Salmonella enterica subsp. enterica GDP-mannose pyrophosphorylase ManC SWALL:Q9EXX7 (EMBL:AY012192) (482 aa) fasta scores: E(): 4.4e-76, 48.45% id in 485 aa, and to Escherichia coli O157:H7 mannose-1-phosphate guanylyltransferase ManC or z3195 or ecs2836 SWALL:MANC_ECO57 (SWALL:O85342) (482 aa) fasta scores: E(): 1.2e-75, 48.14% id in 486 aa. Note: Also similar to BPSL0605 ManC (531 aa) fasta scores: E(): 1.2e-105, 63.843% identity in 484 aa overlap; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
  
 0.656
wcbE
Similar to Pseudomonas aeruginosa glycosyltransferase WbpX or pa5449 SWALL:O84908 (EMBL:AF010181) (460 aa) fasta scores: E(): 1e-09, 34.83% id in 155 aa, and to previously sequenced Burkholderia pseudomallei putative glycosyltransferase WcbE SWALL:Q93UJ8 (EMBL:AF228583) (507 aa) fasta scores: E(): 1e-206, 99.8% id in 507 aa, and to Burkholderia mallei putative glycosyltransferase WcbE SWALL:Q9AI44 (EMBL:AF285636) (507 aa) fasta scores: E(): 7.2e-206, 99.8% id in 507 aa, and to Actinobacillus actinomycetemcomitans putative glycosyltransferase SWALL:Q9JRN4 (EMBL:AB046360) (390 aa) fasta [...]
 
  
 0.604
BPSS1830
Putative exopolysaccharide biosynthesis related tyrosine-protein kinase; Similar to Acinetobacter johnsonii tyrosine-protein kinase Ptk SWALL:PTK_ACIJO (SWALL:O52788) (733 aa) fasta scores: E(): 9.7e-68, 33.1% id in 728 aa, and to Escherichia coli tyrosine-protein kinase Wzc or b2060 SWALL:WZC_ECOLI (SWALL:P76387) (720 aa) fasta scores: E(): 4e-63, 36.25% id in 742 aa.
 
  
 0.603
wbiB
Previously sequenced as Burkholderia pseudomallei putative epimerase/dehydratase WbiB SWALL:O69123 (EMBL:AF064070) (363 aa) fasta scores: E(): 1e-138, 100% id in 363 aa. Also similar to Burkholderia mallei putative epimerase/dehydratase WbiB SWALL:Q9AEV2 (EMBL:AY028370) (363 aa) fasta scores: E(): 2.1e-138, 99.72% id in 363 aa and to Rhizobium loti putative sugar nucleotide epimerase/dehydratase mlr7558 SWALL:Q985R8 (EMBL:AP003012) (352 aa) fasta scores: E(): 1.3e-76, 57.71% id in 350 aa.
 
 
0.583
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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