STRINGSTRING
citB citB icd icd BPSL0890 BPSL0890 gltA gltA aceA aceA sodB sodB prpD prpD prpC prpC rplS rplS rpmB rpmB BPSS0209 BPSS0209
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
citBAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)    
Predicted Functional Partners:
icd
Similar to Alcaligenes eutrophus isocitrate dehydrogenase isozyme 1 Icd1 SWALL:CAD32550 (EMBL:AJ488288) (442 aa) fasta scores: E(): 5.7e-133, 85.81% id in 416 aa, and to Ralstonia solanacearum probable isocitrate dehydrogenase Icd or rsc2490 or rs01106 SWALL:Q8XWI4 (EMBL:AL646070) (416 aa) fasta scores: E(): 2.5e-139, 88.7% id in 416 aa.
 
 0.985
BPSL0890
Putative citrate synthase; C-terminal region is similar to Agrobacterium tumefaciens citrate synthase CisZ or atu4851 or agr_l_71 SWALL:Q8U6F6 (EMBL:AE009414) (335 aa) fasta scores: E(): 6.7e-14, 42.68% id in 335 aa, and to Staphylococcus aureus citrate synthase II CitZ SWALL:Q99TG7 (EMBL:AP003363) (373 aa) fasta scores: E(): 4.7e-13, 27.36% id in 391 aa. Possible alternative translational start site.
 
 0.981
gltA
Citrate synthase; Similar to Rhizobium meliloti citrate synthase GltA or r01509 or smc02087 SWALL:CISY_RHIME (SWALL:O33915) (429 aa) fasta scores: E(): 1.4e-128, 70.23% id in 430 aa, and to Ralstonia solanacearum probable citrate synthase protein rsc1991 or rs03559 SWALL:Q8XXX2 (EMBL:AL646067) (433 aa) fasta scores: E(): 6.9e-149, 82.44% id in 433 aa.
 
 0.980
aceA
Isocitrate lyase; Similar to Escherichia coli, and Escherichia coli O6 isocitrate lyase AceA or Icl or b4015 or c4972 SWALL:ACEA_ECOLI (SWALL:P05313) (434 aa) fasta scores: E(): 6.8e-120, 69.97% id in 433 aa, and to Ralstonia solanacearum probable isocitrate lyase protein rsc1358 or rs04640 SWALL:Q8XZN7 (EMBL:AL646064) (443 aa) fasta scores: E(): 1.6e-149, 85.81% id in 430 aa.
   
 
 0.922
sodB
Putative superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.914
prpD
Similar to Escherichia coli 2-methylcitrate dehydratase PrpD or b0334 SWALL:PRPD_ECOLI (SWALL:P77243) (482 aa) fasta scores: E(): 1e-152, 75.93% id in 482 aa, and to Ralstonia solanacearum probable protein PrpD or rsc2002 or rs03570 SWALL:Q8XXW1 (EMBL:AL646067) (488 aa) fasta scores: E(): 2.9e-159, 78.89% id in 488 aa.
  
 
 0.845
prpC
Similar to Escherichia coli 2-methylcitrate synthase PrpC or b0333 SWALL:PRPC_ECOLI (SWALL:P31660) (389 aa) fasta scores: E(): 3.5e-119, 78.61% id in 374 aa, and to Burkholderia sacchari 2-methylcitrate synthase PrpC SWALL:Q8VPS9 (EMBL:AY033092) (388 aa) fasta scores: E(): 1.2e-133, 86.15% id in 390 aa.
 
 0.843
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
 
 0.797
rpmB
50S ribosomal protein L28; Similar to Escherichia coli, and Escherichia coli O157:H7 50S ribosomal protein L28 RpmB or b3637 or z5061 or ecs4512 SWALL:RL28_ECOLI (SWALL:P02428) (77 aa) fasta scores: E(): 1.1e-20, 73.33% id in 75 aa, and to Ralstonia solanacearum 50S ribosomal protein L28 RpmB or rsc2445 or rs01349 SWALL:RL28_RALSO (SWALL:Q8XWM9) (77 aa) fasta scores: E(): 1.1e-28, 94.73% id in 76 aa, and to Neisseria meningitidis 50S ribosomal protein L28 RpmB or nma2166 or nmb0321 SWALL:RL28_NEIMA (SWALL:Q9JQQ3) (77 aa) fasta scores: E(): 1.7e-27, 90.9% id in 77 aa; Belongs to the bac [...]
   
   0.774
BPSS0209
Putative membrane protein; Similar to Ralstonia solanacearum hypothetical transmembrane protein rsp0119 or rs03003 SWALL:Q8XTI9 (EMBL:AL646076) (396 aa) fasta scores: E(): 2.8e-129, 88.07% id in 394 aa, and to Burkholderia sacchari hypothetical 41.4 kDa protein SWALL:Q8VPS6 (EMBL:AY033092) (396 aa) fasta scores: E(): 4.9e-128, 86.36% id in 396 aa.
 
  
 0.771
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.