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BPSS2286 BPSS2286 rmlB rmlB guaA guaA purL purL BPSL1406 BPSL1406 BPSL1472 BPSL1472 BPSL3323 BPSL3323 rfbH rfbH BPSS0422 BPSS0422 ribB-2 ribB-2 BPSL1964 BPSL1964
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
BPSS2286Hypothetical protein; Poor similarity to Aeropyrum pernix hypothetical protein ape2489 SWALL:Q9Y8Z5 (EMBL:AP000064) (150 aa) fasta scores: E(): 1.6e-10, 39.39% id in 132 aa, and to Pyrobaculum aerophilum conserved protein with 2 CBS domains pae2961 SWALL:Q8ZU39 (EMBL:AE009903) (139 aa) fasta scores: E(): 7.6e-08, 28.98% id in 138 aa. (172 aa)    
Predicted Functional Partners:
rmlB
dTDP-glucose 4,6-dehydratase; Previously sequenced as Burkholderia pseudomallei putative dTDP-D-glucose 4,6-dehydratase RmlB SWALL:O69116 (EMBL:AF064070) (353 aa) fasta scores: E(): 5.6e-143, 100% id in 353 aa and similar to Xanthomonas campestris dTDP-glucose 4,6-dehydratase RfbB or RmlB or xcc0621 SWALL:RFBB_XANCP (SWALL:P55295) (351 aa) fasta scores: E(): 1.2e-88, 66.56% id in 341 aa; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.677
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
  
 0.581
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
     
 0.539
BPSL1406
Hypothetical protein; No significant database matches.
 
   
 0.525
BPSL1472
Putative LPS biosynthesis-related protein; Similar to Escherichia coli lipopolysaccharide biosynthesis protein RffA or WecE or b3791 SWALL:RFFA_ECOLI (SWALL:P27833) (376 aa) fasta scores: E(): 4e-31, 35.09% id in 379 aa, and to Ralstonia solanacearum putative aminotransferase protein rsc1322 or rs02844 SWALL:Q8XZS3 (EMBL:AL646063) (386 aa) fasta scores: E(): 2.2e-102, 67.01% id in 385 aa; Belongs to the DegT/DnrJ/EryC1 family.
   
  
 0.456
BPSL3323
Putative transferase; Similar to Xanthomonas axonopodis nucleotide sugar transaminase VioA or Xac1966 SWALL:AAM36828 (EMBL:AE011831) (369 aa) fasta scores: E(): 7.3e-103, 71.03% id in 366 aa, and to Streptomyces antibioticus dehydratase OleNI SWALL:Q9RR26 (EMBL:AF055579) (393 aa) fasta scores: E(): 6.2e-41, 38.48% id in 369 aa; Belongs to the DegT/DnrJ/EryC1 family.
   
  
 0.456
rfbH
Similar to Salmonella typhimurium lipopolysaccharide biosynthesis protein RfbH or stm2090 SWALL:RFBH_SALTY (SWALL:P26398) (437 aa) fasta scores: E(): 4.6e-120, 64.45% id in 436 aa, and to Yersinia pseudotuberculosis, and Yersinia pseudotuberculosis CDP-4-keto-6-deoxy-D-glucose-3-dehydrase DdhC SWALL:Q05341 (EMBL:AF461770) (437 aa) fasta scores: E(): 1.3e-119, 65.13% id in 436 aa; Belongs to the DegT/DnrJ/EryC1 family.
   
  
 0.456
BPSS0422
Putative aminotransferase; C-terminal region similar to Escherichia coli, and Escherichia coli O157:H7 perosamine synthetase Per or RfbE or z3200 or ecs2841 SWALL:O07849 (EMBL:AF061251) (366 aa) fasta scores: E(): 3.5e-50, 38.76% id in 356 aa and N-terminal region similar to Agrobacterium tumefaciens acetyltransferase atu2080 or agr_c_3768 SWALL:Q8UDP1 (EMBL:Q8UDP1) (177 aa) blastp scores: Score = 39.9 bits (91), Expect = 0.14 Identities = 46/165 (27%), Positives = 70/165 (41%), Gaps = 18/165 (10%); Belongs to the DegT/DnrJ/EryC1 family.
   
  
 0.456
ribB-2
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
  
 
 0.455
BPSL1964
Similar to Ralstonia solanacearum hypothetical protein rsc1563 or rs05250 SWALL:Q8XZ43 (EMBL:AL646065) (151 aa) fasta scores: E(): 6.6e-39, 70.66% id in 150 aa, and to Rhizobium loti hypothetical protein mlr0188 SWALL:Q98ND5 (EMBL:AP002994) (143 aa) fasta scores: E(): 1.1e-09, 33.33% id in 141 aa.
 
     0.415
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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