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carB carB purF purF pyrB pyrB carA carA argG argG pyrC pyrC purQ purQ argF argF guaA guaA uraA uraA pyrD pyrD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
carBCarbamoyl-phosphate synthase, large subunit; Identified by similarity to SP:P00968; match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369. (1077 aa)    
Predicted Functional Partners:
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
 0.999
pyrB
Aspartate carbamoyltransferase; Identified by similarity to SP:P05654; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670.
 
 0.999
carA
Carbamoyl-phosphate synthase, small subunit; Identified by similarity to SP:P25993; match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368.
 0.999
argG
Argininosuccinate synthase; Identified by similarity to GP:20150951; match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 0.997
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
 
 0.997
purQ
Phosphoribosylformylglycinamidine synthase I.
 
 
 0.993
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
 
 0.988
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.984
uraA
Uracil permease; Identified by similarity to SP:P39766; match to protein family HMM PF00860; match to protein family HMM TIGR00801.
  
  
 0.969
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
 
 
 0.968
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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