node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DVU_0295 | DVU_0296 | DVU_0295 | DVU_0296 | Amine oxidase, flavin-containing. | Peptidase, M24 family; Identified by match to protein family HMM PF00557. | 0.612 |
DVU_0296 | DVU_0295 | DVU_0296 | DVU_0295 | Peptidase, M24 family; Identified by match to protein family HMM PF00557. | Amine oxidase, flavin-containing. | 0.612 |
DVU_0296 | DVU_0506 | DVU_0296 | DVU_0506 | Peptidase, M24 family; Identified by match to protein family HMM PF00557. | DHH family protein; Identified by match to protein family HMM PF01368; match to protein family HMM PF02272. | 0.626 |
DVU_0296 | aroQ | DVU_0296 | DVU_1665 | Peptidase, M24 family; Identified by match to protein family HMM PF00557. | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.776 |
DVU_0296 | guaB | DVU_0296 | DVU_1044 | Peptidase, M24 family; Identified by match to protein family HMM PF00557. | Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.571 |
DVU_0296 | hisS | DVU_0296 | DVU_3368 | Peptidase, M24 family; Identified by match to protein family HMM PF00557. | histidyl-tRNA synthetase; Identified by similarity to SP:P04804; match to protein family HMM PF00587; match to protein family HMM PF03129; match to protein family HMM TIGR00442. | 0.472 |
DVU_0296 | metG | DVU_0296 | DVU_2055 | Peptidase, M24 family; Identified by match to protein family HMM PF00557. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.499 |
DVU_0296 | poR | DVU_0296 | DVU_3025 | Peptidase, M24 family; Identified by match to protein family HMM PF00557. | Pyruvate-ferredoxin oxidoreductase; Identified by similarity to GP:1770208; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855. | 0.495 |
DVU_0296 | putA | DVU_0296 | DVU_3319 | Peptidase, M24 family; Identified by match to protein family HMM PF00557. | Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.505 |
DVU_0296 | sucCD | DVU_0296 | DVU_2137 | Peptidase, M24 family; Identified by match to protein family HMM PF00557. | succinyl-CoA synthase, beta/alpha subunits; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.559 |
DVU_0296 | topA | DVU_0296 | DVU_3389 | Peptidase, M24 family; Identified by match to protein family HMM PF00557. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.500 |
DVU_0506 | DVU_0296 | DVU_0506 | DVU_0296 | DHH family protein; Identified by match to protein family HMM PF01368; match to protein family HMM PF02272. | Peptidase, M24 family; Identified by match to protein family HMM PF00557. | 0.626 |
aroQ | DVU_0296 | DVU_1665 | DVU_0296 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Peptidase, M24 family; Identified by match to protein family HMM PF00557. | 0.776 |
guaB | DVU_0296 | DVU_1044 | DVU_0296 | Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Peptidase, M24 family; Identified by match to protein family HMM PF00557. | 0.571 |
guaB | metG | DVU_1044 | DVU_2055 | Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.723 |
guaB | poR | DVU_1044 | DVU_3025 | Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Pyruvate-ferredoxin oxidoreductase; Identified by similarity to GP:1770208; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855. | 0.564 |
guaB | putA | DVU_1044 | DVU_3319 | Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.496 |
guaB | sucCD | DVU_1044 | DVU_2137 | Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | succinyl-CoA synthase, beta/alpha subunits; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.617 |
hisS | DVU_0296 | DVU_3368 | DVU_0296 | histidyl-tRNA synthetase; Identified by similarity to SP:P04804; match to protein family HMM PF00587; match to protein family HMM PF03129; match to protein family HMM TIGR00442. | Peptidase, M24 family; Identified by match to protein family HMM PF00557. | 0.472 |
hisS | metG | DVU_3368 | DVU_2055 | histidyl-tRNA synthetase; Identified by similarity to SP:P04804; match to protein family HMM PF00587; match to protein family HMM PF03129; match to protein family HMM TIGR00442. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.684 |