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pepA pepA glyA glyA cysK cysK DVU_0841 DVU_0841 aspB aspB DVU_0171 DVU_0171 DVU_1585 DVU_1585 DVU_0414 DVU_0414 DVU_0512 DVU_0512 DVU_2239 DVU_2239 gcvT gcvT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pepACytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (507 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family.
  
 
 0.842
cysK
Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
 0.841
DVU_0841
Aspartate aminotransferase, putative; Identified by similarity to GP:15826454; match to protein family HMM PF00155.
  
  0.833
aspB
Aspartate aminotransferase; Identified by similarity to SP:P23034; match to protein family HMM PF00155.
   
  0.822
DVU_0171
Hemolysin-related protein; Identified by similarity to GP:1019859; match to protein family HMM PF00155.
  
 
  0.810
DVU_1585
Vitamin B12-dependent methionine synthase family protein; Identified by similarity to SP:P37586; match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.
 
  
 0.638
DVU_0414
NADP-dependent malic enzyme-related protein; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.
  
  
 0.619
DVU_0512
Flagellar basal-body rod protein, putative; Identified by similarity to SP:P75939; match to protein family HMM PF00460; Belongs to the flagella basal body rod proteins family.
    
   0.616
DVU_2239
Identified by match to protein family HMM PF00933.
    
 0.606
gcvT
Glycine cleavage system T protein; Identified by match to protein family HMM PF01571; match to protein family HMM TIGR00528.
  
  
 0.583
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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