node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DVU_0465 | trpA | DVU_0465 | DVU_0471 | Anthranilate synthase, component I; Identified by similarity to SP:O66849; match to protein family HMM PF00425; match to protein family HMM PF04715. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. | 0.991 |
DVU_0465 | trpB-1 | DVU_0465 | DVU_0085 | Anthranilate synthase, component I; Identified by similarity to SP:O66849; match to protein family HMM PF00425; match to protein family HMM PF04715. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.911 |
DVU_0465 | trpB-2 | DVU_0465 | DVU_0470 | Anthranilate synthase, component I; Identified by similarity to SP:O66849; match to protein family HMM PF00425; match to protein family HMM PF04715. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpB family. | 0.969 |
DVU_0465 | trpC | DVU_0465 | DVU_0468 | Anthranilate synthase, component I; Identified by similarity to SP:O66849; match to protein family HMM PF00425; match to protein family HMM PF04715. | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218. | 0.999 |
DVU_0465 | trpD | DVU_0465 | DVU_0467 | Anthranilate synthase, component I; Identified by similarity to SP:O66849; match to protein family HMM PF00425; match to protein family HMM PF04715. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
DVU_0465 | trpF-1 | DVU_0465 | DVU_0469 | Anthranilate synthase, component I; Identified by similarity to SP:O66849; match to protein family HMM PF00425; match to protein family HMM PF04715. | N-(5'-phosphoribosyl)anthranilate isomerase; Identified by match to protein family HMM PF00697; Belongs to the TrpF family. | 0.972 |
DVU_0465 | trpG | DVU_0465 | DVU_0466 | Anthranilate synthase, component I; Identified by similarity to SP:O66849; match to protein family HMM PF00425; match to protein family HMM PF04715. | Anthranilate synthase, glutamine amidotransferase component; Identified by similarity to SP:Q08654; match to protein family HMM PF00117; match to protein family HMM TIGR00566. | 0.999 |
DVU_3121 | glyA | DVU_3121 | DVU_1203 | Aminotransferase, class V; Identified by match to protein family HMM PF00266. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family. | 0.922 |
DVU_3121 | trpA | DVU_3121 | DVU_0471 | Aminotransferase, class V; Identified by match to protein family HMM PF00266. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. | 0.904 |
DVU_3121 | trpB-1 | DVU_3121 | DVU_0085 | Aminotransferase, class V; Identified by match to protein family HMM PF00266. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.904 |
DVU_3121 | trpB-2 | DVU_3121 | DVU_0470 | Aminotransferase, class V; Identified by match to protein family HMM PF00266. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpB family. | 0.904 |
glyA | DVU_3121 | DVU_1203 | DVU_3121 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family. | Aminotransferase, class V; Identified by match to protein family HMM PF00266. | 0.922 |
glyA | trpA | DVU_1203 | DVU_0471 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. | 0.940 |
glyA | trpB-1 | DVU_1203 | DVU_0085 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.913 |
glyA | trpB-2 | DVU_1203 | DVU_0470 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpB family. | 0.913 |
tnaA | trpA | DVU_2204 | DVU_0471 | Tryptophanase; Identified by similarity to SP:Q59342; match to protein family HMM PF01212; Belongs to the beta-eliminating lyase family. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. | 0.938 |
tnaA | trpB-1 | DVU_2204 | DVU_0085 | Tryptophanase; Identified by similarity to SP:Q59342; match to protein family HMM PF01212; Belongs to the beta-eliminating lyase family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.907 |
tnaA | trpB-2 | DVU_2204 | DVU_0470 | Tryptophanase; Identified by similarity to SP:Q59342; match to protein family HMM PF01212; Belongs to the beta-eliminating lyase family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpB family. | 0.907 |
trpA | DVU_0465 | DVU_0471 | DVU_0465 | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. | Anthranilate synthase, component I; Identified by similarity to SP:O66849; match to protein family HMM PF00425; match to protein family HMM PF04715. | 0.991 |
trpA | DVU_3121 | DVU_0471 | DVU_3121 | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. | Aminotransferase, class V; Identified by match to protein family HMM PF00266. | 0.904 |