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trpB-2 trpB-2 trpC trpC trpA trpA trpD trpD trpF-1 trpF-1 DVU_0465 DVU_0465 trpG trpG trpB-1 trpB-1 glyA glyA tnaA tnaA DVU_3121 DVU_3121
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
trpB-2Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpB family. (395 aa)    
Predicted Functional Partners:
trpC
Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218.
 
 0.999
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
 0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
  
 0.993
trpF-1
N-(5'-phosphoribosyl)anthranilate isomerase; Identified by match to protein family HMM PF00697; Belongs to the TrpF family.
  
 0.989
DVU_0465
Anthranilate synthase, component I; Identified by similarity to SP:O66849; match to protein family HMM PF00425; match to protein family HMM PF04715.
 
  
 0.969
trpG
Anthranilate synthase, glutamine amidotransferase component; Identified by similarity to SP:Q08654; match to protein family HMM PF00117; match to protein family HMM TIGR00566.
  
 0.961
trpB-1
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
0.945
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family.
   
 
 0.913
tnaA
Tryptophanase; Identified by similarity to SP:Q59342; match to protein family HMM PF01212; Belongs to the beta-eliminating lyase family.
     
 0.907
DVU_3121
Aminotransferase, class V; Identified by match to protein family HMM PF00266.
    
 0.904
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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