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ldh ldh poR poR pyk pyk DVU_3349 DVU_3349 DVU_1945 DVU_1945 porA porA sucCD sucCD icd icd DVU_0414 DVU_0414 pgi pgi porB porB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (309 aa)    
Predicted Functional Partners:
poR
Pyruvate-ferredoxin oxidoreductase; Identified by similarity to GP:1770208; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855.
  
 0.996
pyk
Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
  
 0.988
DVU_3349
Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; Identified by match to protein family HMM PF01855.
  
 
 0.979
DVU_1945
Pyruvate ferredoxin oxidoreductase, alpha subunit, putative; Identified by match to protein family HMM PF01855.
  
 
 0.975
porA
Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to GP:43498; match to protein family HMM PF01558; match to protein family HMM PF01855.
  
 
 0.974
sucCD
succinyl-CoA synthase, beta/alpha subunits; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.973
icd
Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF00180; match to protein family HMM TIGR00183.
  
 
 0.967
DVU_0414
NADP-dependent malic enzyme-related protein; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.
  
 0.960
pgi
Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342.
  
 
 0.959
porB
Pyruvate ferredoxin oxidoreductase, beta subunit; Identified by similarity to GP:1565184.
  
 
 0.952
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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