node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DVU_0361 | DVU_1914 | DVU_0361 | DVU_1914 | Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842. | 2-isopropylmalate synthase/homocitrate synthase family protein; Identified by match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.904 |
DVU_0361 | DVU_3293 | DVU_0361 | DVU_3293 | Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842. | Thiamine pyrophosphate-requiring enzyme; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | 0.990 |
DVU_0361 | ilvB-1 | DVU_0361 | DVU_0360 | Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842. | Acetolactate synthase, large subunit, biosynthetic type; Identified by similarity to SP:P08142; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118. | 0.998 |
DVU_0361 | ilvB-2 | DVU_0361 | DVU_1376 | Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842. | Acetolactate synthase, large subunit, biosynthetic type; Identified by similarity to SP:P00893; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118. | 0.989 |
DVU_0361 | ilvC | DVU_0361 | DVU_1378 | Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.979 |
DVU_0361 | ilvN-1 | DVU_0361 | DVU_0626 | Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842. | Acetolactate synthase, small subunit; Identified by similarity to SP:P37252; match to protein family HMM PF01842; match to protein family HMM TIGR00119. | 0.938 |
DVU_0361 | ilvN-2 | DVU_0361 | DVU_1377 | Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842. | Acetolactate synthase, small subunit; Identified by similarity to SP:P00894; match to protein family HMM PF01842; match to protein family HMM TIGR00119. | 0.914 |
DVU_0361 | leuA | DVU_0361 | DVU_2981 | Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.904 |
DVU_0361 | leuB | DVU_0361 | DVU_2985 | Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.972 |
DVU_0361 | poR | DVU_0361 | DVU_3025 | Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842. | Pyruvate-ferredoxin oxidoreductase; Identified by similarity to GP:1770208; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855. | 0.923 |
DVU_1914 | DVU_0361 | DVU_1914 | DVU_0361 | 2-isopropylmalate synthase/homocitrate synthase family protein; Identified by match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842. | 0.904 |
DVU_1914 | DVU_3293 | DVU_1914 | DVU_3293 | 2-isopropylmalate synthase/homocitrate synthase family protein; Identified by match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Thiamine pyrophosphate-requiring enzyme; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | 0.891 |
DVU_1914 | ilvB-1 | DVU_1914 | DVU_0360 | 2-isopropylmalate synthase/homocitrate synthase family protein; Identified by match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetolactate synthase, large subunit, biosynthetic type; Identified by similarity to SP:P08142; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118. | 0.891 |
DVU_1914 | ilvB-2 | DVU_1914 | DVU_1376 | 2-isopropylmalate synthase/homocitrate synthase family protein; Identified by match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetolactate synthase, large subunit, biosynthetic type; Identified by similarity to SP:P00893; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118. | 0.891 |
DVU_1914 | ilvC | DVU_1914 | DVU_1378 | 2-isopropylmalate synthase/homocitrate synthase family protein; Identified by match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.807 |
DVU_1914 | ilvN-1 | DVU_1914 | DVU_0626 | 2-isopropylmalate synthase/homocitrate synthase family protein; Identified by match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetolactate synthase, small subunit; Identified by similarity to SP:P37252; match to protein family HMM PF01842; match to protein family HMM TIGR00119. | 0.922 |
DVU_1914 | ilvN-2 | DVU_1914 | DVU_1377 | 2-isopropylmalate synthase/homocitrate synthase family protein; Identified by match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetolactate synthase, small subunit; Identified by similarity to SP:P00894; match to protein family HMM PF01842; match to protein family HMM TIGR00119. | 0.923 |
DVU_1914 | leuA | DVU_1914 | DVU_2981 | 2-isopropylmalate synthase/homocitrate synthase family protein; Identified by match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.923 |
DVU_1914 | leuB | DVU_1914 | DVU_2985 | 2-isopropylmalate synthase/homocitrate synthase family protein; Identified by match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.862 |
DVU_1914 | poR | DVU_1914 | DVU_3025 | 2-isopropylmalate synthase/homocitrate synthase family protein; Identified by match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Pyruvate-ferredoxin oxidoreductase; Identified by similarity to GP:1770208; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855. | 0.955 |