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ptsI ptsI ptsH ptsH DVU_0981 DVU_0981 DVU_1630 DVU_1630 smpB smpB DVU_0831 DVU_0831 rpoN rpoN DVU_0827 DVU_0827 DVU_1632 DVU_1632 tuf tuf pgk pgk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ptsIPhosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (590 aa)    
Predicted Functional Partners:
ptsH
Phosphocarrier protein HPr; Identified by similarity to SP:P07006; match to protein family HMM PF00381; match to protein family HMM TIGR01003.
 
 0.999
DVU_0981
Multiphosphoryl transfer protein, putative; Identified by similarity to SP:P23388; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF03610; match to protein family HMM PF05524; match to protein family HMM TIGR01003; match to protein family HMM TIGR01417; Belongs to the PEP-utilizing enzyme family.
 
0.993
DVU_1630
PTS system, IIA component; Identified by match to protein family HMM PF00359.
 
  
 0.825
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
  
    0.805
DVU_0831
PTS system, IID component, putative; Identified by similarity to SP:P26382.
 
  
 0.766
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.749
DVU_0827
Glycolate oxidase, subunit GlcD, putative; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.
  
    0.719
DVU_1632
PTS system, IIA component; Identified by similarity to OMNI:BR2094; match to protein family HMM PF03610.
 
  
 0.716
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
    0.591
pgk
Phosphoglycerate kinase; Identified by match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family.
   
  
 0.589
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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