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DVU_0831 DVU_0831 DVU_1632 DVU_1632 DVU_1634 DVU_1634 DVU_1633 DVU_1633 ptsH ptsH DVU_0685 DVU_0685 DVU_0697 DVU_0697 ptsI ptsI smpB smpB DVU_0981 DVU_0981 DVU_1650 DVU_1650
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
DVU_0831PTS system, IID component, putative; Identified by similarity to SP:P26382. (252 aa)    
Predicted Functional Partners:
DVU_1632
PTS system, IIA component; Identified by similarity to OMNI:BR2094; match to protein family HMM PF03610.
 
 0.999
DVU_1634
Membrane protein, putative.
  
 0.999
DVU_1633
PTS system, IIB component; Identified by similarity to SP:P42909; match to protein family HMM PF03830.
 
 
 0.992
ptsH
Phosphocarrier protein HPr; Identified by similarity to SP:P07006; match to protein family HMM PF00381; match to protein family HMM TIGR01003.
  
 
 0.967
DVU_0685
Phosphomannomutase; Identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.
    
 0.903
DVU_0697
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family.
     
  0.900
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.766
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
  
    0.634
DVU_0981
Multiphosphoryl transfer protein, putative; Identified by similarity to SP:P23388; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF03610; match to protein family HMM PF05524; match to protein family HMM TIGR01003; match to protein family HMM TIGR01417; Belongs to the PEP-utilizing enzyme family.
 
  
 0.605
DVU_1650
Conserved hypothetical protein; Identified by similarity to SP:P45576.
  
    0.581
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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