node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DVU_0192 | DVU_2878 | DVU_0192 | DVU_2878 | Adenine specific DNA methyltransferase, putative; Identified by match to protein family HMM PF01555; match to protein family HMM PF02195; Belongs to the N(4)/N(6)-methyltransferase family. | Adenine specific DNA methyltransferase, putative; Identified by match to protein family HMM PF01555; match to protein family HMM PF02195; Belongs to the N(4)/N(6)-methyltransferase family. | 0.880 |
DVU_0192 | dnaA-1 | DVU_0192 | DVU_0001 | Adenine specific DNA methyltransferase, putative; Identified by match to protein family HMM PF01555; match to protein family HMM PF02195; Belongs to the N(4)/N(6)-methyltransferase family. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.453 |
DVU_0192 | gidB | DVU_0192 | DVU_1250 | Adenine specific DNA methyltransferase, putative; Identified by match to protein family HMM PF01555; match to protein family HMM PF02195; Belongs to the N(4)/N(6)-methyltransferase family. | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.780 |
DVU_0192 | gyrA | DVU_0192 | DVU_0004 | Adenine specific DNA methyltransferase, putative; Identified by match to protein family HMM PF01555; match to protein family HMM PF02195; Belongs to the N(4)/N(6)-methyltransferase family. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.496 |
DVU_1078 | dnaN | DVU_1078 | DVU_0002 | R3H domain protein; Identified by match to protein family HMM PF01424. | DNA polymerase III, beta subunit; Identified by match to protein family HMM PF00712; match to protein family HMM PF02768; match to protein family HMM TIGR00663. | 0.703 |
DVU_1078 | gidB | DVU_1078 | DVU_1250 | R3H domain protein; Identified by match to protein family HMM PF01424. | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.713 |
DVU_1078 | trmE | DVU_1078 | DVU_1079 | R3H domain protein; Identified by match to protein family HMM PF01424. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.663 |
DVU_1078 | yidC | DVU_1078 | DVU_1077 | R3H domain protein; Identified by match to protein family HMM PF01424. | Inner membrane protein, 60 kDa; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.944 |
DVU_2878 | DVU_0192 | DVU_2878 | DVU_0192 | Adenine specific DNA methyltransferase, putative; Identified by match to protein family HMM PF01555; match to protein family HMM PF02195; Belongs to the N(4)/N(6)-methyltransferase family. | Adenine specific DNA methyltransferase, putative; Identified by match to protein family HMM PF01555; match to protein family HMM PF02195; Belongs to the N(4)/N(6)-methyltransferase family. | 0.880 |
DVU_2878 | dnaA-1 | DVU_2878 | DVU_0001 | Adenine specific DNA methyltransferase, putative; Identified by match to protein family HMM PF01555; match to protein family HMM PF02195; Belongs to the N(4)/N(6)-methyltransferase family. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.453 |
DVU_2878 | gidB | DVU_2878 | DVU_1250 | Adenine specific DNA methyltransferase, putative; Identified by match to protein family HMM PF01555; match to protein family HMM PF02195; Belongs to the N(4)/N(6)-methyltransferase family. | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.781 |
DVU_2878 | gyrA | DVU_2878 | DVU_0004 | Adenine specific DNA methyltransferase, putative; Identified by match to protein family HMM PF01555; match to protein family HMM PF02195; Belongs to the N(4)/N(6)-methyltransferase family. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.496 |
DVU_3360 | dnaA-1 | DVU_3360 | DVU_0001 | Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.534 |
DVU_3360 | gidB | DVU_3360 | DVU_1250 | Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.709 |
DVU_3360 | trmE | DVU_3360 | DVU_1079 | Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.645 |
dnaA-1 | DVU_0192 | DVU_0001 | DVU_0192 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Adenine specific DNA methyltransferase, putative; Identified by match to protein family HMM PF01555; match to protein family HMM PF02195; Belongs to the N(4)/N(6)-methyltransferase family. | 0.453 |
dnaA-1 | DVU_2878 | DVU_0001 | DVU_2878 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Adenine specific DNA methyltransferase, putative; Identified by match to protein family HMM PF01555; match to protein family HMM PF02195; Belongs to the N(4)/N(6)-methyltransferase family. | 0.453 |
dnaA-1 | DVU_3360 | DVU_0001 | DVU_3360 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | 0.534 |
dnaA-1 | dnaN | DVU_0001 | DVU_0002 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA polymerase III, beta subunit; Identified by match to protein family HMM PF00712; match to protein family HMM PF02768; match to protein family HMM TIGR00663. | 0.984 |
dnaA-1 | gidA | DVU_0001 | DVU_1828 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.472 |