node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DVU_1463 | cbiD | DVU_1463 | DVU_2750 | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.466 |
DVU_1463 | cbiG | DVU_1463 | DVU_3169 | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. | Cobalamin biosynthesis protein CbiG; Identified by similarity to SP:Q05631; match to protein family HMM PF01890. | 0.534 |
DVU_1463 | cbiKc | DVU_1463 | DVU_1365 | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. | Heme-binding protein, putative; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme. | 0.914 |
DVU_1463 | cbiKp | DVU_1463 | DVU_0650 | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. | Chelatase, putative; Catalyzes the insertion of Co(2+) into sirohydrochlorin. To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme. Its periplasmic location means that it cannot participate in cobalamin biosynthesis and its genomic environment suggests it is likely to be associated with a heme or metal transport system. | 0.914 |
DVU_1463 | cobI | DVU_1463 | DVU_0646 | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. | Precorrin-2 C20-methyltransferase; Identified by similarity to SP:Q05593; match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family. | 0.943 |
DVU_1463 | cobL | DVU_1463 | DVU_2749 | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. | precorrin-6Y C5,15-methyltransferase (decarboxylating); Identified by similarity to SP:P21921; match to protein family HMM PF00590; match to protein family HMM TIGR01468. | 0.604 |
DVU_1463 | cobM | DVU_1463 | DVU_2748 | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. | Precorrin-4 C11-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465. | 0.650 |
cbiD | DVU_1463 | DVU_2750 | DVU_1463 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. | 0.466 |
cbiD | cbiG | DVU_2750 | DVU_3169 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Cobalamin biosynthesis protein CbiG; Identified by similarity to SP:Q05631; match to protein family HMM PF01890. | 0.999 |
cbiD | cbiKc | DVU_2750 | DVU_1365 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Heme-binding protein, putative; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme. | 0.852 |
cbiD | cbiKp | DVU_2750 | DVU_0650 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Chelatase, putative; Catalyzes the insertion of Co(2+) into sirohydrochlorin. To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme. Its periplasmic location means that it cannot participate in cobalamin biosynthesis and its genomic environment suggests it is likely to be associated with a heme or metal transport system. | 0.857 |
cbiD | cobH | DVU_2750 | DVU_3087 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | precorrin-8X methylmutase; Identified by similarity to GP:15826199; match to protein family HMM PF02570. | 0.995 |
cbiD | cobI | DVU_2750 | DVU_0646 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Precorrin-2 C20-methyltransferase; Identified by similarity to SP:Q05593; match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family. | 0.972 |
cbiD | cobJ | DVU_2750 | DVU_3170 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Precorrin-3b C17-methyltransferase; Identified by similarity to SP:P21640; match to protein family HMM PF00590; match to protein family HMM TIGR01466. | 0.944 |
cbiD | cobL | DVU_2750 | DVU_2749 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | precorrin-6Y C5,15-methyltransferase (decarboxylating); Identified by similarity to SP:P21921; match to protein family HMM PF00590; match to protein family HMM TIGR01468. | 0.993 |
cbiD | cobM | DVU_2750 | DVU_2748 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Precorrin-4 C11-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465. | 0.957 |
cbiD | cobQ | DVU_2750 | DVU_0816 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.928 |
cbiG | DVU_1463 | DVU_3169 | DVU_1463 | Cobalamin biosynthesis protein CbiG; Identified by similarity to SP:Q05631; match to protein family HMM PF01890. | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. | 0.534 |
cbiG | cbiD | DVU_3169 | DVU_2750 | Cobalamin biosynthesis protein CbiG; Identified by similarity to SP:Q05631; match to protein family HMM PF01890. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.999 |
cbiG | cbiKc | DVU_3169 | DVU_1365 | Cobalamin biosynthesis protein CbiG; Identified by similarity to SP:Q05631; match to protein family HMM PF01890. | Heme-binding protein, putative; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme. | 0.941 |