node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DVU_1036 | lpdA | DVU_1036 | DVU_1423 | Membrane protein, putative. | 2-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to SP:O34324; match to protein family HMM PF00070; match to protein family HMM PF02852. | 0.907 |
DVU_2272 | DVU_2824 | DVU_2272 | DVU_2824 | Formate acetyltransferase, putative; Identified by similarity to SP:P32674; match to protein family HMM PF01228; match to protein family HMM PF02901. | Formate acetyltransferase; Identified by match to protein family HMM PF01228; match to protein family HMM PF02901. | 0.934 |
DVU_2272 | lpdA | DVU_2272 | DVU_1423 | Formate acetyltransferase, putative; Identified by similarity to SP:P32674; match to protein family HMM PF01228; match to protein family HMM PF02901. | 2-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to SP:O34324; match to protein family HMM PF00070; match to protein family HMM PF02852. | 0.906 |
DVU_2272 | poR | DVU_2272 | DVU_3025 | Formate acetyltransferase, putative; Identified by similarity to SP:P32674; match to protein family HMM PF01228; match to protein family HMM PF02901. | Pyruvate-ferredoxin oxidoreductase; Identified by similarity to GP:1770208; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855. | 0.955 |
DVU_2272 | porA | DVU_2272 | DVU_1569 | Formate acetyltransferase, putative; Identified by similarity to SP:P32674; match to protein family HMM PF01228; match to protein family HMM PF02901. | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to GP:43498; match to protein family HMM PF01558; match to protein family HMM PF01855. | 0.937 |
DVU_2824 | DVU_2272 | DVU_2824 | DVU_2272 | Formate acetyltransferase; Identified by match to protein family HMM PF01228; match to protein family HMM PF02901. | Formate acetyltransferase, putative; Identified by similarity to SP:P32674; match to protein family HMM PF01228; match to protein family HMM PF02901. | 0.934 |
DVU_2824 | lpdA | DVU_2824 | DVU_1423 | Formate acetyltransferase; Identified by match to protein family HMM PF01228; match to protein family HMM PF02901. | 2-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to SP:O34324; match to protein family HMM PF00070; match to protein family HMM PF02852. | 0.906 |
DVU_2824 | poR | DVU_2824 | DVU_3025 | Formate acetyltransferase; Identified by match to protein family HMM PF01228; match to protein family HMM PF02901. | Pyruvate-ferredoxin oxidoreductase; Identified by similarity to GP:1770208; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855. | 0.955 |
DVU_2824 | porA | DVU_2824 | DVU_1569 | Formate acetyltransferase; Identified by match to protein family HMM PF01228; match to protein family HMM PF02901. | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to GP:43498; match to protein family HMM PF01558; match to protein family HMM PF01855. | 0.937 |
gcvH | gcvPA | DVU_1426 | DVU_1425 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily. | 0.999 |
gcvH | gcvPB | DVU_1426 | DVU_1424 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system P protein, subunit 2; Identified by similarity to SP:P54377; Belongs to the GcvP family. | 0.999 |
gcvH | gcvT | DVU_1426 | DVU_1684 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system T protein; Identified by match to protein family HMM PF01571; match to protein family HMM TIGR00528. | 0.999 |
gcvH | glyA | DVU_1426 | DVU_1203 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family. | 0.990 |
gcvH | lpdA | DVU_1426 | DVU_1423 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 2-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to SP:O34324; match to protein family HMM PF00070; match to protein family HMM PF02852. | 0.995 |
gcvPA | gcvH | DVU_1425 | DVU_1426 | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
gcvPA | gcvPB | DVU_1425 | DVU_1424 | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily. | Glycine cleavage system P protein, subunit 2; Identified by similarity to SP:P54377; Belongs to the GcvP family. | 0.999 |
gcvPA | gcvT | DVU_1425 | DVU_1684 | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily. | Glycine cleavage system T protein; Identified by match to protein family HMM PF01571; match to protein family HMM TIGR00528. | 0.999 |
gcvPA | glyA | DVU_1425 | DVU_1203 | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family. | 0.976 |
gcvPA | lpdA | DVU_1425 | DVU_1423 | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily. | 2-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to SP:O34324; match to protein family HMM PF00070; match to protein family HMM PF02852. | 0.989 |
gcvPB | gcvH | DVU_1424 | DVU_1426 | Glycine cleavage system P protein, subunit 2; Identified by similarity to SP:P54377; Belongs to the GcvP family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |