STRINGSTRING
fbp fbp tkt tkt pfkA pfkA pgi pgi fba fba DVU_0697 DVU_0697 DVU_1658 DVU_1658 aroA-2 aroA-2 glpX glpX tsaD tsaD gap-2 gap-2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
fbpFructose-1,6-bisphosphatase; Identified by match to protein family HMM PF00316. (337 aa)    
Predicted Functional Partners:
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
 
 
 0.971
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
    
 0.961
pgi
Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342.
   
 
 0.960
fba
Fructose-1,6-bisphosphate aldolase, class II; Identified by similarity to SP:P13243; match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859.
  
 
 0.956
DVU_0697
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 0.953
DVU_1658
Transaldolase, putative; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.947
aroA-2
Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids; Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
    
 0.923
glpX
Fructose-1,6-bisphosphatase, class II; Identified by similarity to SP:P28860; match to protein family HMM PF03320; match to protein family HMM TIGR00330; Belongs to the FBPase class 2 family.
  
 
 0.920
tsaD
Metalloendopeptidase, putative, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.
  
    0.704
gap-2
Glyceraldehyde 3-phosphate dehydrogenase; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534.
  
  
 0.696
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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