node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DVU_0082 | ltaE | DVU_0082 | DVU_1878 | Conserved hypothetical protein; Identified by similarity to GP:12543284. | Threonine aldolase, low-specificity; Identified by similarity to SP:O50584. | 0.416 |
DVU_1879 | ltaE | DVU_1879 | DVU_1878 | Glycosyl transferase, group 1 family protein; Identified by match to protein family HMM PF00534. | Threonine aldolase, low-specificity; Identified by similarity to SP:O50584. | 0.768 |
DVU_3121 | gcvPA | DVU_3121 | DVU_1425 | Aminotransferase, class V; Identified by match to protein family HMM PF00266. | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily. | 0.900 |
DVU_3121 | gcvPB | DVU_3121 | DVU_1424 | Aminotransferase, class V; Identified by match to protein family HMM PF00266. | Glycine cleavage system P protein, subunit 2; Identified by similarity to SP:P54377; Belongs to the GcvP family. | 0.912 |
DVU_3121 | glyA | DVU_3121 | DVU_1203 | Aminotransferase, class V; Identified by match to protein family HMM PF00266. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family. | 0.922 |
DVU_3121 | ltaE | DVU_3121 | DVU_1878 | Aminotransferase, class V; Identified by match to protein family HMM PF00266. | Threonine aldolase, low-specificity; Identified by similarity to SP:O50584. | 0.914 |
DVU_3121 | putA | DVU_3121 | DVU_3319 | Aminotransferase, class V; Identified by match to protein family HMM PF00266. | Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.449 |
gcvPA | DVU_3121 | DVU_1425 | DVU_3121 | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily. | Aminotransferase, class V; Identified by match to protein family HMM PF00266. | 0.900 |
gcvPA | gcvPB | DVU_1425 | DVU_1424 | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily. | Glycine cleavage system P protein, subunit 2; Identified by similarity to SP:P54377; Belongs to the GcvP family. | 0.999 |
gcvPA | glyA | DVU_1425 | DVU_1203 | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family. | 0.976 |
gcvPA | ltaE | DVU_1425 | DVU_1878 | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily. | Threonine aldolase, low-specificity; Identified by similarity to SP:O50584. | 0.922 |
gcvPA | putA | DVU_1425 | DVU_3319 | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily. | Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.827 |
gcvPB | DVU_3121 | DVU_1424 | DVU_3121 | Glycine cleavage system P protein, subunit 2; Identified by similarity to SP:P54377; Belongs to the GcvP family. | Aminotransferase, class V; Identified by match to protein family HMM PF00266. | 0.912 |
gcvPB | gcvPA | DVU_1424 | DVU_1425 | Glycine cleavage system P protein, subunit 2; Identified by similarity to SP:P54377; Belongs to the GcvP family. | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily. | 0.999 |
gcvPB | glyA | DVU_1424 | DVU_1203 | Glycine cleavage system P protein, subunit 2; Identified by similarity to SP:P54377; Belongs to the GcvP family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family. | 0.988 |
gcvPB | ltaE | DVU_1424 | DVU_1878 | Glycine cleavage system P protein, subunit 2; Identified by similarity to SP:P54377; Belongs to the GcvP family. | Threonine aldolase, low-specificity; Identified by similarity to SP:O50584. | 0.924 |
gcvPB | putA | DVU_1424 | DVU_3319 | Glycine cleavage system P protein, subunit 2; Identified by similarity to SP:P54377; Belongs to the GcvP family. | Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.878 |
glyA | DVU_3121 | DVU_1203 | DVU_3121 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family. | Aminotransferase, class V; Identified by match to protein family HMM PF00266. | 0.922 |
glyA | gcvPA | DVU_1203 | DVU_1425 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family. | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily. | 0.976 |
glyA | gcvPB | DVU_1203 | DVU_1424 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family. | Glycine cleavage system P protein, subunit 2; Identified by similarity to SP:P54377; Belongs to the GcvP family. | 0.988 |