STRINGSTRING
thiS thiS DVU_2092 DVU_2092 thiG thiG DVU_0643 DVU_0643 thiH thiH thiE-1 thiE-1 thiC thiC thiD thiD thiE-2 thiE-2 ThiH ThiH DVU_3241 DVU_3241
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiSThiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683. (66 aa)    
Predicted Functional Partners:
DVU_2092
Identified by match to protein family HMM PF00899.
 
 0.998
thiG
thiG protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S; Belongs to the ThiG family.
 
 
 0.994
DVU_0643
thiF protein, putative; Identified by similarity to SP:P30138; match to protein family HMM PF00899.
  
 0.990
thiH
thiH protein; Identified by similarity to SP:P30140; match to protein family HMM PF04055.
  
  
 0.931
thiE-1
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
 
  
 0.853
thiC
Thiamine biosynthesis protein ThiC; Identified by match to protein family HMM PF01964; match to protein family HMM TIGR00190.
  
  
 0.826
thiD
Phosphomethylpyrimidine kinase; Identified by match to protein family HMM TIGR00097.
  
    0.793
thiE-2
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.722
ThiH
thiH protein, putative; Identified by similarity to SP:P30140; match to protein family HMM PF04055.
  
  
 0.698
DVU_3241
Conserved hypothetical protein; Identified by similarity to OMNI:NTL03CP0990; match to protein family HMM PF01171.
  
 
 0.629
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
Server load: low (26%) [HD]