node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
adk | cmk | DVU_1932 | DVU_1028 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | 0.514 |
adk | gpt | DVU_1932 | DVU_1066 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.569 |
adk | guaA | DVU_1932 | DVU_1043 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.660 |
adk | guaB | DVU_1932 | DVU_1044 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.460 |
adk | purA | DVU_1932 | DVU_3204 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.460 |
adk | purB | DVU_1932 | DVU_2942 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenylosuccinate lyase; Identified by similarity to SP:P12047; match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.961 |
adk | pyrH | DVU_1932 | DVU_0871 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.683 |
adk | surE | DVU_1932 | DVU_2142 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.922 |
adk | tmk | DVU_1932 | DVU_2140 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.436 |
cmk | adk | DVU_1028 | DVU_1932 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.514 |
cmk | guaA | DVU_1028 | DVU_1043 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.605 |
cmk | guaB | DVU_1028 | DVU_1044 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.555 |
cmk | pyrF | DVU_1028 | DVU_0901 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Orotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.468 |
cmk | pyrH | DVU_1028 | DVU_0871 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.517 |
cmk | surE | DVU_1028 | DVU_2142 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.926 |
cmk | tmk | DVU_1028 | DVU_2140 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.421 |
gpt | adk | DVU_1066 | DVU_1932 | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.569 |
gpt | guaA | DVU_1066 | DVU_1043 | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.996 |
gpt | guaB | DVU_1066 | DVU_1044 | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.955 |
gpt | purA | DVU_1066 | DVU_3204 | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.748 |