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thiM thiM thiE-1 thiE-1 thiE-2 thiE-2 thiD thiD ThiH ThiH thiH thiH thiG thiG thiC thiC thiS thiS DVU_1157 DVU_1157 DVU_2361 DVU_2361
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (267 aa)    
Predicted Functional Partners:
thiE-1
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
 
 0.999
thiE-2
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.999
thiD
Phosphomethylpyrimidine kinase; Identified by match to protein family HMM TIGR00097.
  
 0.995
ThiH
thiH protein, putative; Identified by similarity to SP:P30140; match to protein family HMM PF04055.
  
  
 0.777
thiH
thiH protein; Identified by similarity to SP:P30140; match to protein family HMM PF04055.
  
  
 0.774
thiG
thiG protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S; Belongs to the ThiG family.
  
  
 0.765
thiC
Thiamine biosynthesis protein ThiC; Identified by match to protein family HMM PF01964; match to protein family HMM TIGR00190.
  
  
 0.761
thiS
Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683.
  
    0.611
DVU_1157
Sensory box histidine kinase; Identified by match to protein family HMM PF02518; match to protein family HMM TIGR00229.
  
    0.578
DVU_2361
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.556
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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