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birA birA bioB bioB DVU_2226 DVU_2226 DVU_1767 DVU_1767 DVU_1835 DVU_1835 DVU_1834 DVU_1834 bioA bioA DVU_0864 DVU_0864 DVU_2224 DVU_2224 xth xth DVU_1653 DVU_1653
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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birAbirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (330 aa)    
Predicted Functional Partners:
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.974
DVU_2226
acetyl-CoA carboxylase, biotin carboxylase, putative; Identified by match to protein family HMM PF00289; match to protein family HMM PF02786.
 
 0.970
DVU_1767
Radical SAM domain protein; Identified by match to protein family HMM PF04055.
  
 
 0.953
DVU_1835
biotin--acetyl-CoA-carboxylase ligase; Identified by match to protein family HMM PF03099; match to protein family HMM TIGR00121.
 
 
 
0.934
DVU_1834
Pyruvate carboxylase, putative; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
 
 0.933
bioA
Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
 
   
 0.911
DVU_0864
Glycoprotease family protein, putative; Identified by match to protein family HMM PF00814.
  
    0.907
DVU_2224
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.886
xth
Exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633.
  
    0.861
DVU_1653
Identified by similarity to SP:P42977; match to protein family HMM PF00571; match to protein family HMM PF01368; match to protein family HMM PF01743; match to protein family HMM PF02272; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.846
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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