STRINGSTRING
DVU_2828 DVU_2828 DVU_1667 DVU_1667 topA topA DVU_3360 DVU_3360 DVU_2768 DVU_2768 gpt gpt DVU_3358 DVU_3358 DVU_0464 DVU_0464 recR recR DVU_2075 DVU_2075 dnaA-2 dnaA-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
DVU_2828Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589; Belongs to the 'phage' integrase family. (394 aa)    
Predicted Functional Partners:
DVU_1667
Identified by match to protein family HMM PF01580.
 
   
 0.665
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.664
DVU_3360
Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family.
  
  
 0.595
DVU_2768
comF family protein; Identified by similarity to SP:P31773.
   
    0.523
gpt
Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
   
    0.493
DVU_3358
Identified by match to protein family HMM PF00991.
 
  
 0.493
DVU_0464
Prephenate dehydrogenase; Identified by match to protein family HMM PF02153.
  
    0.489
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
   
 0.489
DVU_2075
Identified by match to protein family HMM PF00991.
 
   
 0.470
dnaA-2
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
  
   
 0.443
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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