node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DVU_0656 | ubiE | DVU_0656 | DVU_3174 | Conserved hypothetical protein; Identified by similarity to OMNI:NTL02SC2888; match to protein family HMM PF03966; Belongs to the UPF0434 family. | Ubiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.443 |
DVU_1767 | bioB | DVU_1767 | DVU_2558 | Radical SAM domain protein; Identified by match to protein family HMM PF04055. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.909 |
DVU_1767 | bioF | DVU_1767 | DVU_2564 | Radical SAM domain protein; Identified by match to protein family HMM PF04055. | 8-amino-7-oxononanoate synthase; Identified by similarity to SP:P22806. | 0.779 |
DVU_1767 | ubiE | DVU_1767 | DVU_3174 | Radical SAM domain protein; Identified by match to protein family HMM PF04055. | Ubiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.479 |
DVU_2320 | ubiE | DVU_2320 | DVU_3174 | Identified by match to protein family HMM PF01977. | Ubiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.604 |
DVU_3172 | DVU_3173 | DVU_3172 | DVU_3173 | Hypothetical protein; Identified by Glimmer2; putative. | Hypothetical protein; Identified by Glimmer2; putative. | 0.457 |
DVU_3172 | ubiE | DVU_3172 | DVU_3174 | Hypothetical protein; Identified by Glimmer2; putative. | Ubiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.452 |
DVU_3173 | DVU_3172 | DVU_3173 | DVU_3172 | Hypothetical protein; Identified by Glimmer2; putative. | Hypothetical protein; Identified by Glimmer2; putative. | 0.457 |
DVU_3173 | ubiE | DVU_3173 | DVU_3174 | Hypothetical protein; Identified by Glimmer2; putative. | Ubiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.804 |
bioB | DVU_1767 | DVU_2558 | DVU_1767 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Radical SAM domain protein; Identified by match to protein family HMM PF04055. | 0.909 |
bioB | bioF | DVU_2558 | DVU_2564 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 8-amino-7-oxononanoate synthase; Identified by similarity to SP:P22806. | 0.952 |
bioB | ubiE | DVU_2558 | DVU_3174 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Ubiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.484 |
bioF | DVU_1767 | DVU_2564 | DVU_1767 | 8-amino-7-oxononanoate synthase; Identified by similarity to SP:P22806. | Radical SAM domain protein; Identified by match to protein family HMM PF04055. | 0.779 |
bioF | bioB | DVU_2564 | DVU_2558 | 8-amino-7-oxononanoate synthase; Identified by similarity to SP:P22806. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.952 |
bioF | ubiE | DVU_2564 | DVU_3174 | 8-amino-7-oxononanoate synthase; Identified by similarity to SP:P22806. | Ubiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.423 |
ispB | ubiE | DVU_3179 | DVU_3174 | Octaprenyl-diphosphate synthase; Identified by similarity to SP:P19641; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Ubiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.411 |
lipA | ubiE | DVU_0905 | DVU_3174 | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Ubiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.516 |
queE | ubiE | DVU_2658 | DVU_3174 | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Ubiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.735 |
ubiE | DVU_0656 | DVU_3174 | DVU_0656 | Ubiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | Conserved hypothetical protein; Identified by similarity to OMNI:NTL02SC2888; match to protein family HMM PF03966; Belongs to the UPF0434 family. | 0.443 |
ubiE | DVU_1767 | DVU_3174 | DVU_1767 | Ubiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | Radical SAM domain protein; Identified by match to protein family HMM PF04055. | 0.479 |