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hup-4 hup-4 DVU_2973 DVU_2973 DVU_1864 DVU_1864 DVU_1422 DVU_1422 rbO rbO hup-1 hup-1 DVU_3186 DVU_3186 topA topA rpsT rpsT DVU_0462 DVU_0462 rpsO rpsO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hup-4DNA-binding protein HU; Identified by similarity to SP:P02341; similar to SP:P08821; similar to GP:14028719; match to protein family HMM PF00216; Belongs to the bacterial histone-like protein family. (95 aa)    
Predicted Functional Partners:
DVU_2973
Integration host factor, beta subunit; Identified by similarity to SP:Q06607; match to protein family HMM PF00216.
 
  
 0.851
DVU_1864
DNA-binding protein HU, beta subunit, putative; Identified by similarity to SP:P08821; match to protein family HMM PF00216.
  
 
 0.816
DVU_1422
Identified by match to protein family HMM PF00691.
   
 
 0.752
rbO
Desulfoferrodoxin; Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity; Belongs to the desulfoferrodoxin family.
   
    0.748
hup-1
DNA-binding protein HU; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
  
 
0.701
DVU_3186
Hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.599
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.556
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
  
 0.539
DVU_0462
Chorismate mutase/prephenate dehydratase; Identified by similarity to SP:P07022; match to protein family HMM PF00800; match to protein family HMM PF01817; match to protein family HMM PF01842; match to protein family HMM TIGR01807.
  
  
 0.517
rpsO
Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
   
  
 0.515
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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