node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DVU_2188 | engA | DVU_2188 | DVU_3194 | Primase, putative; Identified by match to protein family HMM PF01751; match to protein family HMM PF03288; match to protein family HMM TIGR01613. | GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.737 |
cmk | engA | DVU_1028 | DVU_3194 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.977 |
cmk | ffh | DVU_1028 | DVU_0840 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 0.758 |
cmk | ftsY | DVU_1028 | DVU_3059 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.492 |
cmk | gpsA | DVU_1028 | DVU_3159 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Glycerol-3-phosphate dehydrogenase (NAD(P)+); Identified by similarity to SP:P37606; match to protein family HMM PF01210; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.471 |
cmk | rluB | DVU_1028 | DVU_1669 | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Ribosomal large subunit pseudouridine synthase B; Identified by similarity to SP:P35159; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; Belongs to the pseudouridine synthase RsuA family. | 0.915 |
dnaG | engA | DVU_1789 | DVU_3194 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.799 |
dnaG | rluB | DVU_1789 | DVU_1669 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Ribosomal large subunit pseudouridine synthase B; Identified by similarity to SP:P35159; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; Belongs to the pseudouridine synthase RsuA family. | 0.762 |
dnaG | rluD/coaE | DVU_1789 | DVU_1024 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Ribosomal large subunit pseudouridine synthase D/dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.511 |
dnaG | secA | DVU_1789 | DVU_0825 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.543 |
engA | DVU_2188 | DVU_3194 | DVU_2188 | GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Primase, putative; Identified by match to protein family HMM PF01751; match to protein family HMM PF03288; match to protein family HMM TIGR01613. | 0.737 |
engA | cmk | DVU_3194 | DVU_1028 | GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Cytidylate kinase; Identified by similarity to SP:P23863; match to protein family HMM PF02224; match to protein family HMM TIGR00017. | 0.977 |
engA | dnaG | DVU_3194 | DVU_1789 | GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.799 |
engA | ffh | DVU_3194 | DVU_0840 | GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 0.719 |
engA | frr | DVU_3194 | DVU_0870 | GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.738 |
engA | ftsY | DVU_3194 | DVU_3059 | GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.737 |
engA | gpsA | DVU_3194 | DVU_3159 | GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Glycerol-3-phosphate dehydrogenase (NAD(P)+); Identified by similarity to SP:P37606; match to protein family HMM PF01210; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.967 |
engA | rluB | DVU_3194 | DVU_1669 | GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Ribosomal large subunit pseudouridine synthase B; Identified by similarity to SP:P35159; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; Belongs to the pseudouridine synthase RsuA family. | 0.901 |
engA | rluD/coaE | DVU_3194 | DVU_1024 | GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Ribosomal large subunit pseudouridine synthase D/dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.790 |
engA | secA | DVU_3194 | DVU_0825 | GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.747 |