STRINGSTRING
Dbac_0833 Dbac_0833 Dbac_1044 Dbac_1044 leuB leuB Dbac_2425 Dbac_2425 leuA leuA Dbac_0188 Dbac_0188 Dbac_0109 Dbac_0109 acsA acsA Dbac_3166 Dbac_3166 glcB glcB Dbac_0088 Dbac_0088
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dbac_0833PFAM: pyruvate carboxyltransferase; KEGG: dvu:DVUA0016 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (373 aa)    
Predicted Functional Partners:
Dbac_1044
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
 
 0.947
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 
 0.925
Dbac_2425
TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: dde:Dde_2049 alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
  
 
0.925
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
  
 
0.923
Dbac_0188
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: dde:Dde_1792 pyruvate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.919
Dbac_0109
PFAM: AMP-dependent synthetase and ligase; KEGG: dvu:DVU2250 AMP-binding protein.
  
 
 0.915
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.915
Dbac_3166
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 
 0.915
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 
 0.909
Dbac_0088
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dvl:Dvul_1223 2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
   
 
 0.906
Your Current Organism:
Desulfomicrobium baculatum
NCBI taxonomy Id: 525897
Other names: D. baculatum DSM 4028, Desulfomicrobium baculatum DSM 4028, Desulfomicrobium baculatum str. DSM 4028, Desulfomicrobium baculatum strain DSM 4028
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.