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Dde_0001 Dde_0001 Dde_0002 Dde_0002 dnaA dnaA Dde_1409 Dde_1409 gmhA gmhA Dde_3061 Dde_3061 Dde_3404 Dde_3404 gyrB gyrB Dde_0031 Dde_0031 rnpA rnpA Dde_0374 Dde_0374
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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Dde_0001Chromosomal replication initiator DnaA domain-containing protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (436 aa)    
Predicted Functional Partners:
Dde_0002
SMART: DNA polymerase III, beta chain; TIGRFAM: DNA polymerase III, beta chain; KEGG: dvl:Dvul_0006 subunit beta; PFAM: DNA polymerase III, beta chain.
  
 
 0.974
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
  
  
 
0.914
Dde_1409
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
   
 
 0.813
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
    
 
 0.707
Dde_3061
KEGG: dvl:Dvul_0481 aminopeptidase 1; PFAM: Peptidase M18, aminopeptidase I.
 
      0.694
Dde_3404
KEGG: elm:ELI_1642 hypothetical protein.
   
 
 0.676
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.609
Dde_0031
PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: dvm:DvMF_2047 cobyrinic acid ac-diamide synthase.
 
 
 0.602
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
  
 0.594
Dde_0374
CoA-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Pyridine nucleotide-disulfide oxidoreductase, NAD-binding region; Pyridine nucleotide-disulfide oxidoreductase, dimerisation; KEGG: dvl:Dvul_0176 FAD-dependent pyridine nucleotide-disulfide oxidoreductase; SMART: Rhodanese-like.
  
    0.584
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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