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Dde_0039 Dde_0039 coaD coaD coaX coaX panC panC Dde_2453 Dde_2453 Dde_3596 Dde_3596 Dde_2932 Dde_2932 Dde_1103 Dde_1103 Dde_3080 Dde_3080 Dde_0038 Dde_0038 Dde_0040 Dde_0040
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
Dde_0039Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (408 aa)    
Predicted Functional Partners:
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.948
coaX
Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
 
 
 0.938
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 
 0.912
Dde_2453
MazG family protein; KEGG: dvu:DVU1186 nucleoside triphosphate pyrophosphohydrolase; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core.
     
  0.900
Dde_3596
Aspartate transaminase; KEGG: dvl:Dvul_0165 aminotransferase, class I and II; PFAM: Aminotransferase, class I/II.
 
  0.857
Dde_2932
KEGG: dvm:DvMF_2690 hypothetical protein.
     
 0.856
Dde_1103
KEGG: dvm:DvMF_2889 aspartate aminotransferase; PFAM: Aminotransferase, class I/II.
  
  0.834
Dde_3080
TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; KEGG: dvm:DvMF_2658 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.828
Dde_0038
KEGG: dvu:DVU4021 hypothetical protein.
       0.804
Dde_0040
KEGG: drt:Dret_2496 putative lipoprotein.
       0.804
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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