STRINGSTRING
Dde_0070 Dde_0070 Dde_2708 Dde_2708 Dde_3159 Dde_3159 grpE grpE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Dde_0070KEGG: das:Daes_0976 STE24 endopeptidase; PFAM: Peptidase M48, Ste24p. (427 aa)    
Predicted Functional Partners:
Dde_2708
KEGG: dvm:DvMF_1396 flagellar motor switch protein FliM; TIGRFAM: Flagellar motor switch protein FliM; PFAM: Flagellar motor switch protein FliM; Surface presentation of antigen (SpoA).
    
   0.623
Dde_3159
KEGG: dvl:Dvul_2429 hypothetical protein; TIGRFAM: Flagellar basal-body rod FlgF; Fagellar hook-basal body protein, FlgE/F/G; PFAM: Flagellar basal body rod protein, N-terminal; Protein of unknown function DUF1078, C-terminal.
    
   0.623
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.515
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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