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trpB trpB trpA trpA Dde_3481 Dde_3481 trpF-2 trpF-2 trpD trpD trpB-2 trpB-2 glyA glyA Dde_3034 Dde_3034 Dde_3111 Dde_3111 Dde_3217 Dde_3217 Dde_3484 Dde_3484
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (382 aa)    
Predicted Functional Partners:
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 0.999
Dde_3481
KEGG: dma:DMR_05280 indole-3-glycerol phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase.
 
 0.998
trpF-2
KEGG: dvm:DvMF_1742 phosphoribosylanthranilate isomerase; PFAM: N-5'phosphoribosylanthranilate isomerase (PRAI); Belongs to the TrpF family.
  
 0.966
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
  
 0.960
trpB-2
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 
 
0.918
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.913
Dde_3034
KEGG: das:Daes_0636 L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain.
     
  0.900
Dde_3111
L-serine ammonia-lyase; KEGG: dsa:Desal_2312 serine dehydratase alpha chain; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.900
Dde_3217
KEGG: dvm:DvMF_1790 CDP-diacylglycerol/serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
  0.900
Dde_3484
KEGG: dvm:DvMF_1746 anthranilate synthase; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal.
 
  
 0.894
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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