node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dde_0503 | Dde_0504 | Dde_0503 | Dde_0504 | HPP family protein; PFAM: HPP; KEGG: dvl:Dvul_0138 HPP family protein+B94. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.546 |
Dde_0503 | Dde_0505 | Dde_0503 | Dde_0505 | HPP family protein; PFAM: HPP; KEGG: dvl:Dvul_0138 HPP family protein+B94. | TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; KEGG: dvm:DvMF_1700 PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; PAC motif. | 0.464 |
Dde_0503 | Dde_0511 | Dde_0503 | Dde_0511 | HPP family protein; PFAM: HPP; KEGG: dvl:Dvul_0138 HPP family protein+B94. | KEGG: dvl:Dvul_0238 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; 6-phosphofructo-2-kinase; SMART: Phosphoglycerate mutase. | 0.401 |
Dde_0503 | Dde_2337 | Dde_0503 | Dde_2337 | HPP family protein; PFAM: HPP; KEGG: dvl:Dvul_0138 HPP family protein+B94. | PFAM: Histone deacetylase superfamily; KEGG: dvm:DvMF_0024 histone deacetylase superfamily. | 0.581 |
Dde_0503 | glmS | Dde_0503 | Dde_0502 | HPP family protein; PFAM: HPP; KEGG: dvl:Dvul_0138 HPP family protein+B94. | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.531 |
Dde_0503 | guaA | Dde_0503 | Dde_1470 | HPP family protein; PFAM: HPP; KEGG: dvl:Dvul_0138 HPP family protein+B94. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.831 |
Dde_0504 | Dde_0503 | Dde_0504 | Dde_0503 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | HPP family protein; PFAM: HPP; KEGG: dvl:Dvul_0138 HPP family protein+B94. | 0.546 |
Dde_0504 | Dde_0505 | Dde_0504 | Dde_0505 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; KEGG: dvm:DvMF_1700 PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; PAC motif. | 0.694 |
Dde_0504 | glmS | Dde_0504 | Dde_0502 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.567 |
Dde_0504 | guaA | Dde_0504 | Dde_1470 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.973 |
Dde_0505 | Dde_0503 | Dde_0505 | Dde_0503 | TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; KEGG: dvm:DvMF_1700 PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; PAC motif. | HPP family protein; PFAM: HPP; KEGG: dvl:Dvul_0138 HPP family protein+B94. | 0.464 |
Dde_0505 | Dde_0504 | Dde_0505 | Dde_0504 | TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; KEGG: dvm:DvMF_1700 PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; PAC motif. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.694 |
Dde_0511 | Dde_0503 | Dde_0511 | Dde_0503 | KEGG: dvl:Dvul_0238 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; 6-phosphofructo-2-kinase; SMART: Phosphoglycerate mutase. | HPP family protein; PFAM: HPP; KEGG: dvl:Dvul_0138 HPP family protein+B94. | 0.401 |
Dde_2337 | Dde_0503 | Dde_2337 | Dde_0503 | PFAM: Histone deacetylase superfamily; KEGG: dvm:DvMF_0024 histone deacetylase superfamily. | HPP family protein; PFAM: HPP; KEGG: dvl:Dvul_0138 HPP family protein+B94. | 0.581 |
glmS | Dde_0503 | Dde_0502 | Dde_0503 | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | HPP family protein; PFAM: HPP; KEGG: dvl:Dvul_0138 HPP family protein+B94. | 0.531 |
glmS | Dde_0504 | Dde_0502 | Dde_0504 | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.567 |
glmS | guaA | Dde_0502 | Dde_1470 | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.579 |
guaA | Dde_0503 | Dde_1470 | Dde_0503 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | HPP family protein; PFAM: HPP; KEGG: dvl:Dvul_0138 HPP family protein+B94. | 0.831 |
guaA | Dde_0504 | Dde_1470 | Dde_0504 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.973 |
guaA | glmS | Dde_1470 | Dde_0502 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.579 |