node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dde_0542 | Dde_0544 | Dde_0542 | Dde_0544 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Belongs to the FPG family. | KEGG: dsa:Desal_2870 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker [...] | 0.511 |
Dde_0542 | murJ | Dde_0542 | Dde_0543 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Belongs to the FPG family. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.754 |
Dde_0544 | Dde_0542 | Dde_0544 | Dde_0542 | KEGG: dsa:Desal_2870 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker [...] | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Belongs to the FPG family. | 0.511 |
Dde_0544 | murJ | Dde_0544 | Dde_0543 | KEGG: dsa:Desal_2870 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker [...] | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.589 |
Dde_1041 | mraY | Dde_1041 | Dde_1039 | KEGG: dvm:DvMF_0957 cell division protein FtsW; TIGRFAM: Cell division protein FtsW; PFAM: Cell cycle protein; Belongs to the SEDS family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.985 |
Dde_1041 | mrdB | Dde_1041 | Dde_0992 | KEGG: dvm:DvMF_0957 cell division protein FtsW; TIGRFAM: Cell division protein FtsW; PFAM: Cell cycle protein; Belongs to the SEDS family. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.409 |
Dde_1041 | murA | Dde_1041 | Dde_0546 | KEGG: dvm:DvMF_0957 cell division protein FtsW; TIGRFAM: Cell division protein FtsW; PFAM: Cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.849 |
Dde_1041 | murC | Dde_1041 | Dde_1043 | KEGG: dvm:DvMF_0957 cell division protein FtsW; TIGRFAM: Cell division protein FtsW; PFAM: Cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.991 |
Dde_1041 | murJ | Dde_1041 | Dde_0543 | KEGG: dvm:DvMF_0957 cell division protein FtsW; TIGRFAM: Cell division protein FtsW; PFAM: Cell cycle protein; Belongs to the SEDS family. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.521 |
Dde_3159 | mraY | Dde_3159 | Dde_1039 | KEGG: dvl:Dvul_2429 hypothetical protein; TIGRFAM: Flagellar basal-body rod FlgF; Fagellar hook-basal body protein, FlgE/F/G; PFAM: Flagellar basal body rod protein, N-terminal; Protein of unknown function DUF1078, C-terminal. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.623 |
Dde_3159 | murC | Dde_3159 | Dde_1043 | KEGG: dvl:Dvul_2429 hypothetical protein; TIGRFAM: Flagellar basal-body rod FlgF; Fagellar hook-basal body protein, FlgE/F/G; PFAM: Flagellar basal body rod protein, N-terminal; Protein of unknown function DUF1078, C-terminal. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.437 |
Dde_3159 | murJ | Dde_3159 | Dde_0543 | KEGG: dvl:Dvul_2429 hypothetical protein; TIGRFAM: Flagellar basal-body rod FlgF; Fagellar hook-basal body protein, FlgE/F/G; PFAM: Flagellar basal body rod protein, N-terminal; Protein of unknown function DUF1078, C-terminal. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.533 |
Dde_3505 | murJ | Dde_3505 | Dde_0543 | Riboflavin biosynthesis protein RibF; SMART: Riboflavin kinase; TIGRFAM: Riboflavin kinase/FAD synthetase; KEGG: dvm:DvMF_1762 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.687 |
mraY | Dde_1041 | Dde_1039 | Dde_1041 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | KEGG: dvm:DvMF_0957 cell division protein FtsW; TIGRFAM: Cell division protein FtsW; PFAM: Cell cycle protein; Belongs to the SEDS family. | 0.985 |
mraY | Dde_3159 | Dde_1039 | Dde_3159 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | KEGG: dvl:Dvul_2429 hypothetical protein; TIGRFAM: Flagellar basal-body rod FlgF; Fagellar hook-basal body protein, FlgE/F/G; PFAM: Flagellar basal body rod protein, N-terminal; Protein of unknown function DUF1078, C-terminal. | 0.623 |
mraY | mrdB | Dde_1039 | Dde_0992 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.780 |
mraY | murA | Dde_1039 | Dde_0546 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.845 |
mraY | murC | Dde_1039 | Dde_1043 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.991 |
mraY | murJ | Dde_1039 | Dde_0543 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.507 |
mrdB | Dde_1041 | Dde_0992 | Dde_1041 | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | KEGG: dvm:DvMF_0957 cell division protein FtsW; TIGRFAM: Cell division protein FtsW; PFAM: Cell cycle protein; Belongs to the SEDS family. | 0.409 |