node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dde_0335 | mqnB | Dde_0335 | Dde_3188 | KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ; KEGG: dvm:DvMF_2308 KpsF/GutQ family protein; PFAM: Sugar isomerase (SIS); Cystathionine beta-synthase, core; Belongs to the SIS family. GutQ/KpsF subfamily. | Futalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.401 |
Dde_0335 | mqnD | Dde_0335 | Dde_0799 | KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ; KEGG: dvm:DvMF_2308 KpsF/GutQ family protein; PFAM: Sugar isomerase (SIS); Cystathionine beta-synthase, core; Belongs to the SIS family. GutQ/KpsF subfamily. | Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.442 |
Dde_0795 | mqnA | Dde_0795 | Dde_0796 | KEGG: adn:Alide_0970 hypothetical protein. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.596 |
Dde_0795 | mqnC | Dde_0795 | Dde_0797 | KEGG: adn:Alide_0970 hypothetical protein. | FO synthase, subunit 2; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.599 |
Dde_0795 | mqnD | Dde_0795 | Dde_0799 | KEGG: adn:Alide_0970 hypothetical protein. | Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.411 |
Dde_0795 | mqnE | Dde_0795 | Dde_0798 | KEGG: adn:Alide_0970 hypothetical protein. | FO synthase, subunit 2; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.599 |
Dde_1323 | Dde_1392 | Dde_1323 | Dde_1392 | PFAM: Carboxylyase-related; KEGG: dvl:Dvul_0938 carboxylyase-like protein; Belongs to the UbiD family. | KEGG: dvl:Dvul_2015 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family. | 0.990 |
Dde_1323 | mqnA | Dde_1323 | Dde_0796 | PFAM: Carboxylyase-related; KEGG: dvl:Dvul_0938 carboxylyase-like protein; Belongs to the UbiD family. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.863 |
Dde_1323 | mqnB | Dde_1323 | Dde_3188 | PFAM: Carboxylyase-related; KEGG: dvl:Dvul_0938 carboxylyase-like protein; Belongs to the UbiD family. | Futalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.801 |
Dde_1323 | mqnC | Dde_1323 | Dde_0797 | PFAM: Carboxylyase-related; KEGG: dvl:Dvul_0938 carboxylyase-like protein; Belongs to the UbiD family. | FO synthase, subunit 2; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.774 |
Dde_1323 | mqnD | Dde_1323 | Dde_0799 | PFAM: Carboxylyase-related; KEGG: dvl:Dvul_0938 carboxylyase-like protein; Belongs to the UbiD family. | Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.791 |
Dde_1323 | mqnE | Dde_1323 | Dde_0798 | PFAM: Carboxylyase-related; KEGG: dvl:Dvul_0938 carboxylyase-like protein; Belongs to the UbiD family. | FO synthase, subunit 2; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.760 |
Dde_1323 | ubiX | Dde_1323 | Dde_0150 | PFAM: Carboxylyase-related; KEGG: dvl:Dvul_0938 carboxylyase-like protein; Belongs to the UbiD family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.995 |
Dde_1392 | Dde_1323 | Dde_1392 | Dde_1323 | KEGG: dvl:Dvul_2015 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family. | PFAM: Carboxylyase-related; KEGG: dvl:Dvul_0938 carboxylyase-like protein; Belongs to the UbiD family. | 0.990 |
Dde_1392 | mqnA | Dde_1392 | Dde_0796 | KEGG: dvl:Dvul_2015 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.875 |
Dde_1392 | mqnB | Dde_1392 | Dde_3188 | KEGG: dvl:Dvul_2015 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family. | Futalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.820 |
Dde_1392 | mqnC | Dde_1392 | Dde_0797 | KEGG: dvl:Dvul_2015 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family. | FO synthase, subunit 2; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.815 |
Dde_1392 | mqnD | Dde_1392 | Dde_0799 | KEGG: dvl:Dvul_2015 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family. | Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.821 |
Dde_1392 | mqnE | Dde_1392 | Dde_0798 | KEGG: dvl:Dvul_2015 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family. | FO synthase, subunit 2; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.803 |
Dde_1392 | ubiX | Dde_1392 | Dde_0150 | KEGG: dvl:Dvul_2015 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.986 |