STRINGSTRING
Dde_1089 Dde_1089 Dde_1090 Dde_1090 Dde_1180 Dde_1180 Dde_1773 Dde_1773 Dde_1091 Dde_1091 smpB smpB Dde_1775 Dde_1775 rsmI rsmI Dde_1093 Dde_1093 rnhB rnhB Dde_1776 Dde_1776
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dde_1089Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (592 aa)    
Predicted Functional Partners:
Dde_1090
KEGG: dvm:DvMF_2878 phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein; PFAM: Phosphotransferase system, phosphocarrier HPr protein.
 
 0.999
Dde_1180
TIGRFAM: Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, phosphocarrier HPr protein; Dihydroxyacetone kinase, subunit phosphotransferase; KEGG: dvm:DvMF_2584 phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilising enzyme; Phosphotransferase system, PEP-utilising enzyme, N-terminal; PEP-utilising enzyme, mobile region; Phosphotransferase system, phosphocarrier HPr protein; Phosphotransferase system, fructose subfamily IIA component; Belongs to the PEP-utilizing enzyme family.
 
0.992
Dde_1773
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; KEGG: das:Daes_1477 phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2.
 
  
 0.832
Dde_1091
PFAM: Phosphotransferase system, mannose/fructose/sorbose family IID component; KEGG: dvm:DvMF_2879 PTS system mannose/fructose/sorbose family IID component.
 
   
 0.750
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
  
    0.740
Dde_1775
PFAM: Phosphotransferase system, fructose subfamily IIA component; KEGG: dvl:Dvul_1501 PTS system fructose subfamily IIA component.
 
  
 0.731
rsmI
Protein of unknown function UPF0011; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.636
Dde_1093
PFAM: Uncharacterized protein family UPF0102; KEGG: dvm:DvMF_2881 hypothetical protein; Belongs to the UPF0102 family.
       0.636
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
       0.636
Dde_1776
PFAM: Phosphotransferase system, sorbose subfamily IIB component; KEGG: dvm:DvMF_0422 PTS system sorbose subfamily IIB component.
 
  
 0.574
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.