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Dde_1409 Dde_1409 dnaG dnaG dnaA dnaA rplI rplI Dde_2908 Dde_2908 Dde_3406 Dde_3406 dnaX dnaX rpsR rpsR Dde_0001 Dde_0001 Dde_0907 Dde_0907 Dde_1921 Dde_1921
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Dde_1409Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (493 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 0.912
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
 
 
 
 0.883
rplI
50S ribosomal protein L9; Binds to the 23S rRNA.
 
  
 0.871
Dde_2908
KEGG: gme:Gmet_3281 transposase/IS protein; PFAM: IstB-like ATP-binding protein; SMART: ATPase, AAA+ type, core.
  
 
 0.845
Dde_3406
KEGG: gme:Gmet_3281 transposase/IS protein; PFAM: IstB-like ATP-binding protein; SMART: ATPase, AAA+ type, core.
  
 
 0.845
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 
 0.844
rpsR
Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
 
  
 0.835
Dde_0001
Chromosomal replication initiator DnaA domain-containing protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
   
 
 0.813
Dde_0907
PFAM: DNA primase, catalytic core, N-terminal; KEGG: geb:GM18_2979 DNA primase catalytic core domain-containing protein.
  
 
 0.805
Dde_1921
PFAM: DNA primase, catalytic core, N-terminal; KEGG: sfu:Sfum_3790 DNA primase catalytic core.
  
 
 0.805
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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