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proC proC Dde_0054 Dde_0054 Dde_3055 Dde_3055 proB proB proA proA ndk ndk guaA guaA Dde_1438 Dde_1438 Dde_0547 Dde_0547 Dde_3590 Dde_3590 argD argD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (267 aa)    
Predicted Functional Partners:
Dde_0054
Proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
 0.960
Dde_3055
PFAM: Pyruvate formate-lyase, PFL; Formate C-acetyltransferase glycine radical; KEGG: cno:NT01CX_1220 pyruvate formate-lyase.
    
 0.906
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.870
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.864
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
       0.804
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.628
Dde_1438
PFAM: Protein of unknown function DUF610, YibQ; KEGG: dvu:DVU2335 hypothetical protein.
       0.614
Dde_0547
TIGRFAM: ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; KEGG: das:Daes_1194 DNA internalization-like competence protein ComEC/Rec2; SMART: Beta-lactamase-like.
     
 0.600
Dde_3590
Protein of unknown function UPF0001; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
 
  
 0.592
argD
TIGRFAM: Acetylornithine/succinylornithine aminotransferase; KEGG: dvu:DVU2347 acetylornithine aminotransferase; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
  
 0.585
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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