STRINGSTRING
Dde_1537 Dde_1537 Dde_2112 Dde_2112 Dde_0760 Dde_0760 Dde_0140 Dde_0140 gpt gpt upp upp Dde_1489 Dde_1489 ade ade surE surE pyrR pyrR Dde_0789 Dde_0789
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dde_1537Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (276 aa)    
Predicted Functional Partners:
Dde_2112
TIGRFAM: Hypoxanthine phosphoribosyl transferase; KEGG: dvl:Dvul_1545 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.937
Dde_0760
PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: pao:Pat9b_4202 inosine/uridine-preferring nucleoside hydrolase.
  
 0.934
Dde_0140
PFAM: Phosphoribosyltransferase; KEGG: dra:DR_0878 adenine phosphoribosyltransferase.
  
 
 0.931
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
  
 
 0.931
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.929
Dde_1489
KEGG: dvl:Dvul_2001 ribokinase-like domain-containing protein; PFAM: Carbohydrate/purine kinase.
   
 0.928
ade
TIGRFAM: Adenine deaminase; KEGG: dba:Dbac_1063 adenine deaminase; PFAM: Amidohydrolase 1; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
    
 0.905
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.903
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.901
Dde_0789
5'-nucleotidase; KEGG: tin:Tint_0959 5'-nucleotidase; PFAM: 5-nucleotidase.
     
  0.900
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.