STRINGSTRING
Dde_1932 Dde_1932 recA recA Dde_1930 Dde_1930 Dde_1931 Dde_1931 Dde_2973 Dde_2973 dinB dinB Dde_0891 Dde_0891 Dde_2596 Dde_2596 Dde_0892 Dde_0892 Dde_1941 Dde_1941 topA topA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Dde_1932SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response). (207 aa)    
Predicted Functional Partners:
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.939
Dde_1930
KEGG: dbr:Deba_1839 hypothetical protein.
 
     0.851
Dde_1931
KEGG: sfu:Sfum_3780 hypothetical protein.
 
     0.838
Dde_2973
DNA-directed DNA polymerase; KEGG: dvu:DVU2906 UmuC protein; PFAM: DNA-repair protein, UmuC-like.
 
 
 0.790
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
 
 0.776
Dde_0891
KEGG: dol:Dole_0435 hypothetical protein.
 
     0.615
Dde_2596
SMC domain protein; May be involved in recombinational repair of damaged DNA.
   
  
 0.615
Dde_0892
KEGG: dly:Dehly_1699 hypothetical protein.
 
     0.544
Dde_1941
KEGG: mgm:Mmc1_3271 PAS/PAC sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: Signal transduction response regulator, receiver region; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like.
     
 0.488
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
  
 0.475
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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