node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dde_1514 | Dde_1616 | Dde_1514 | Dde_1616 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | KEGG: dvl:Dvul_0509 metallo-beta-lactamase family protein. | 0.913 |
Dde_1514 | Dde_1969 | Dde_1514 | Dde_1969 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | KEGG: dvl:Dvul_1430 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | 0.998 |
Dde_1514 | Dde_2434 | Dde_1514 | Dde_2434 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.647 |
Dde_1514 | Dde_3058 | Dde_1514 | Dde_3058 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | KEGG: dvm:DvMF_1310 FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family. | 0.998 |
Dde_1514 | birA | Dde_1514 | Dde_2654 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.605 |
Dde_1514 | ribBA | Dde_1514 | Dde_2436 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.534 |
Dde_1616 | Dde_1514 | Dde_1616 | Dde_1514 | KEGG: dvl:Dvul_0509 metallo-beta-lactamase family protein. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.913 |
Dde_1616 | Dde_1969 | Dde_1616 | Dde_1969 | KEGG: dvl:Dvul_0509 metallo-beta-lactamase family protein. | KEGG: dvl:Dvul_1430 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | 0.900 |
Dde_1968 | Dde_1969 | Dde_1968 | Dde_1969 | KEGG: dvm:DvMF_0363 TRASH domain protein. | KEGG: dvl:Dvul_1430 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | 0.742 |
Dde_1968 | Dde_1972 | Dde_1968 | Dde_1972 | KEGG: dvm:DvMF_0363 TRASH domain protein. | PFAM: Polynucleotide adenylyltransferase region; Cystathionine beta-synthase, core; Phosphoesterase, DHHA1; Phosphoesterase, RecJ-like; KEGG: dvl:Dvul_1433 polynucleotide adenylyltransferase region; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.479 |
Dde_1968 | dapL | Dde_1968 | Dde_1970 | KEGG: dvm:DvMF_0363 TRASH domain protein. | LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. | 0.581 |
Dde_1969 | Dde_1514 | Dde_1969 | Dde_1514 | KEGG: dvl:Dvul_1430 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.998 |
Dde_1969 | Dde_1616 | Dde_1969 | Dde_1616 | KEGG: dvl:Dvul_1430 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | KEGG: dvl:Dvul_0509 metallo-beta-lactamase family protein. | 0.900 |
Dde_1969 | Dde_1968 | Dde_1969 | Dde_1968 | KEGG: dvl:Dvul_1430 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | KEGG: dvm:DvMF_0363 TRASH domain protein. | 0.742 |
Dde_1969 | Dde_1972 | Dde_1969 | Dde_1972 | KEGG: dvl:Dvul_1430 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | PFAM: Polynucleotide adenylyltransferase region; Cystathionine beta-synthase, core; Phosphoesterase, DHHA1; Phosphoesterase, RecJ-like; KEGG: dvl:Dvul_1433 polynucleotide adenylyltransferase region; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.729 |
Dde_1969 | Dde_2434 | Dde_1969 | Dde_2434 | KEGG: dvl:Dvul_1430 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.712 |
Dde_1969 | Dde_3058 | Dde_1969 | Dde_3058 | KEGG: dvl:Dvul_1430 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | KEGG: dvm:DvMF_1310 FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family. | 0.720 |
Dde_1969 | birA | Dde_1969 | Dde_2654 | KEGG: dvl:Dvul_1430 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.624 |
Dde_1969 | dapL | Dde_1969 | Dde_1970 | KEGG: dvl:Dvul_1430 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. | 0.629 |
Dde_1969 | nadE | Dde_1969 | Dde_2091 | KEGG: dvl:Dvul_1430 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.612 |