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pdxJ pdxJ Dde_2742 Dde_2742 Dde_2283 Dde_2283 Dde_0127 Dde_0127 acpS acpS nnrE nnrE Dde_2046 Dde_2046 Dde_2047 Dde_2047 ribBA ribBA Dde_2434 Dde_2434 guaA guaA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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pdxJPyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (241 aa)    
Predicted Functional Partners:
Dde_2742
PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: dvu:DVU0769 pyridoxamine kinase; Belongs to the pyridoxine kinase family.
     
 0.904
Dde_2283
4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; KEGG: dvm:DvMF_0837 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; Belongs to the PdxA family.
 
 
 0.895
Dde_0127
PdxA-like dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; KEGG: ttr:Tter_2423 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family.
 
 
 0.865
acpS
Phosphopantetheine-protein transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
  
  
 0.846
nnrE
YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]
     
 0.717
Dde_2046
KEGG: dvm:DvMF_0278 CBS domain containing membrane protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
       0.647
Dde_2047
Uncharacterized protein family UPF0079, ATPase; KEGG: dvm:DvMF_0277 protein of unknown function UPF0079; TIGRFAM: Uncharacterized protein family UPF0079, ATPase bacteria; PFAM: Uncharacterized protein family UPF0079, ATPase bacteria.
       0.624
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.622
Dde_2434
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.615
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
 
   
 0.610
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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