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nnrE nnrE Dde_2047 Dde_2047 Dde_0152 Dde_0152 Dde_0341 Dde_0341 Dde_2480 Dde_2480 Dde_2046 Dde_2046 groL groL acpS acpS Dde_3237 Dde_3237 pdxJ pdxJ Dde_1256 Dde_1256
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
nnrEYjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (548 aa)    
Predicted Functional Partners:
Dde_2047
Uncharacterized protein family UPF0079, ATPase; KEGG: dvm:DvMF_0277 protein of unknown function UPF0079; TIGRFAM: Uncharacterized protein family UPF0079, ATPase bacteria; PFAM: Uncharacterized protein family UPF0079, ATPase bacteria.
  
 
 0.963
Dde_0152
KEGG: dvm:DvMF_2125 DEAD/DEAH box helicase domain protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; DbpA, RNA-binding; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Belongs to the DEAD box helicase family.
  
 0.850
Dde_0341
KEGG: dvm:DvMF_2252 DEAD/DEAH box helicase domain protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Belongs to the DEAD box helicase family.
  
 0.850
Dde_2480
DEAD/DEAH box helicase domain protein; KEGG: dvu:DVU1982 ATP-dependent RNA helicase RhlE; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal.
  
 0.850
Dde_2046
KEGG: dvm:DvMF_0278 CBS domain containing membrane protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
       0.828
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
   0.790
acpS
Phosphopantetheine-protein transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
       0.744
Dde_3237
SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Pyruvate/ketoisovalerate oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
   0.744
pdxJ
Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
     
 0.717
Dde_1256
KEGG: drt:Dret_1067 fumarate reductase iron-sulfur subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein.
  
  
 0.705
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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