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radA radA recA recA Dde_2111 Dde_2111 uvrC uvrC Dde_2112 Dde_2112 Dde_2115 Dde_2115 Dde_3571 Dde_3571 Dde_2113 Dde_2113 Dde_2114 Dde_2114 ispDF ispDF Dde_2596 Dde_2596
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (452 aa)    
Predicted Functional Partners:
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
  
 0.810
Dde_2111
MJ0042 family finger-like protein; TIGRFAM: Zinc finger/thioredoxin putative; KEGG: dvl:Dvul_1544 zinc finger-domain-containing protein.
       0.777
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
  
 0.704
Dde_2112
TIGRFAM: Hypoxanthine phosphoribosyl transferase; KEGG: dvl:Dvul_1545 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
       0.693
Dde_2115
Methionine synthase; KEGG: dvm:DvMF_0476 homocysteine S-methyltransferase; PFAM: Homocysteine S-methyltransferase; Dihydropteroate synthase, DHPS; Methionine synthase, cobalamin (vitamin B12)-binding module, cap; Cobalamin (vitamin B12)-binding.
       0.683
Dde_3571
PFAM: DNA helicase, UvrD/REP type; KEGG: dvm:DvMF_1967 UvrD/REP helicase.
   
  
 0.679
Dde_2113
PFAM: GCN5-related N-acetyltransferase; KEGG: dvm:DvMF_0474 acetyltransferase; Belongs to the acetyltransferase family.
       0.649
Dde_2114
PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: dvm:DvMF_0475 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen.
       0.649
ispDF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
  
  
 0.640
Dde_2596
SMC domain protein; May be involved in recombinational repair of damaged DNA.
  
   
 0.631
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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