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glnD glnD Dde_2310 Dde_2310 Dde_3493 Dde_3493 Dde_2311 Dde_2311 Dde_3078 Dde_3078 nadE nadE guaA guaA cbiA cbiA cbiA-2 cbiA-2 Dde_0104 Dde_0104 guaB guaB
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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glnDUTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. (872 aa)    
Predicted Functional Partners:
Dde_2310
PFAM: Nitrogen regulatory protein PII; KEGG: dvl:Dvul_1830 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 0.995
Dde_3493
PFAM: Nitrogen regulatory protein PII; KEGG: dsa:Desal_3067 nitrogen regulatory protein P-II.
 
 
 0.977
Dde_2311
KEGG: dvm:DvMF_0866 ammonium transporter; TIGRFAM: Ammonium transporter; PFAM: Ammonium transporter.
     
 0.705
Dde_3078
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
     
 0.589
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.501
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
   
  
 0.483
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
   
    0.481
cbiA-2
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
   
    0.481
Dde_0104
TIGRFAM: Glutamine synthetase type I; KEGG: dvm:DvMF_2099 glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp.
     
 0.469
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.439
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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