node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dde_3011 | adk | Dde_3011 | Dde_2028 | KEGG: dvm:DvMF_1468 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.957 |
Dde_3011 | guaA | Dde_3011 | Dde_1470 | KEGG: dvm:DvMF_1468 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.917 |
Dde_3011 | guaB | Dde_3011 | Dde_1471 | KEGG: dvm:DvMF_1468 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.890 |
Dde_3011 | purA | Dde_3011 | Dde_0176 | KEGG: dvm:DvMF_1468 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.996 |
Dde_3011 | pyrF | Dde_3011 | Dde_2718 | KEGG: dvm:DvMF_1468 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.581 |
Dde_3011 | pyrH | Dde_3011 | Dde_1129 | KEGG: dvm:DvMF_1468 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.465 |
Dde_3011 | surE | Dde_3011 | Dde_2340 | KEGG: dvm:DvMF_1468 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.926 |
adk | Dde_3011 | Dde_2028 | Dde_3011 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | KEGG: dvm:DvMF_1468 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.957 |
adk | cmk | Dde_2028 | Dde_1452 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: dvm:DvMF_0909 cytidylate kinase; PFAM: Cytidylate kinase region. | 0.428 |
adk | guaA | Dde_2028 | Dde_1470 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.645 |
adk | guaB | Dde_2028 | Dde_1471 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.458 |
adk | purA | Dde_2028 | Dde_0176 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.436 |
adk | pyrH | Dde_2028 | Dde_1129 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.672 |
adk | surE | Dde_2028 | Dde_2340 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.920 |
adk | tmk | Dde_2028 | Dde_2338 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.439 |
cmk | adk | Dde_1452 | Dde_2028 | TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: dvm:DvMF_0909 cytidylate kinase; PFAM: Cytidylate kinase region. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.428 |
cmk | guaA | Dde_1452 | Dde_1470 | TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: dvm:DvMF_0909 cytidylate kinase; PFAM: Cytidylate kinase region. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.598 |
cmk | guaB | Dde_1452 | Dde_1471 | TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: dvm:DvMF_0909 cytidylate kinase; PFAM: Cytidylate kinase region. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.591 |
cmk | pyrF | Dde_1452 | Dde_2718 | TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: dvm:DvMF_0909 cytidylate kinase; PFAM: Cytidylate kinase region. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.469 |
cmk | pyrH | Dde_1452 | Dde_1129 | TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: dvm:DvMF_0909 cytidylate kinase; PFAM: Cytidylate kinase region. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.505 |