node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dde_0002 | Dde_2596 | Dde_0002 | Dde_2596 | SMART: DNA polymerase III, beta chain; TIGRFAM: DNA polymerase III, beta chain; KEGG: dvl:Dvul_0006 subunit beta; PFAM: DNA polymerase III, beta chain. | SMC domain protein; May be involved in recombinational repair of damaged DNA. | 0.622 |
Dde_0002 | radA | Dde_0002 | Dde_2110 | SMART: DNA polymerase III, beta chain; TIGRFAM: DNA polymerase III, beta chain; KEGG: dvl:Dvul_0006 subunit beta; PFAM: DNA polymerase III, beta chain. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.466 |
Dde_0002 | recA | Dde_0002 | Dde_2373 | SMART: DNA polymerase III, beta chain; TIGRFAM: DNA polymerase III, beta chain; KEGG: dvl:Dvul_0006 subunit beta; PFAM: DNA polymerase III, beta chain. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.904 |
Dde_0002 | topA | Dde_0002 | Dde_0106 | SMART: DNA polymerase III, beta chain; TIGRFAM: DNA polymerase III, beta chain; KEGG: dvl:Dvul_0006 subunit beta; PFAM: DNA polymerase III, beta chain. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.709 |
Dde_1932 | Dde_2596 | Dde_1932 | Dde_2596 | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response). | SMC domain protein; May be involved in recombinational repair of damaged DNA. | 0.615 |
Dde_1932 | recA | Dde_1932 | Dde_2373 | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response). | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.939 |
Dde_1932 | topA | Dde_1932 | Dde_0106 | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response). | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.475 |
Dde_2596 | Dde_0002 | Dde_2596 | Dde_0002 | SMC domain protein; May be involved in recombinational repair of damaged DNA. | SMART: DNA polymerase III, beta chain; TIGRFAM: DNA polymerase III, beta chain; KEGG: dvl:Dvul_0006 subunit beta; PFAM: DNA polymerase III, beta chain. | 0.622 |
Dde_2596 | Dde_1932 | Dde_2596 | Dde_1932 | SMC domain protein; May be involved in recombinational repair of damaged DNA. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response). | 0.615 |
Dde_2596 | Dde_2597 | Dde_2596 | Dde_2597 | SMC domain protein; May be involved in recombinational repair of damaged DNA. | KEGG: dvm:DvMF_0924 hypothetical protein. | 0.695 |
Dde_2596 | Dde_2974 | Dde_2596 | Dde_2974 | SMC domain protein; May be involved in recombinational repair of damaged DNA. | PFAM: Peptidase S24/S26A/S26B, conserved region; KEGG: dvl:Dvul_0458 prophage repressor; Belongs to the peptidase S24 family. | 0.614 |
Dde_2596 | lexA | Dde_2596 | Dde_0893 | SMC domain protein; May be involved in recombinational repair of damaged DNA. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.615 |
Dde_2596 | mfd | Dde_2596 | Dde_2039 | SMC domain protein; May be involved in recombinational repair of damaged DNA. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.633 |
Dde_2596 | radA | Dde_2596 | Dde_2110 | SMC domain protein; May be involved in recombinational repair of damaged DNA. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.631 |
Dde_2596 | recA | Dde_2596 | Dde_2373 | SMC domain protein; May be involved in recombinational repair of damaged DNA. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.849 |
Dde_2596 | ruvA | Dde_2596 | Dde_2323 | SMC domain protein; May be involved in recombinational repair of damaged DNA. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.726 |
Dde_2596 | topA | Dde_2596 | Dde_0106 | SMC domain protein; May be involved in recombinational repair of damaged DNA. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.677 |
Dde_2597 | Dde_2596 | Dde_2597 | Dde_2596 | KEGG: dvm:DvMF_0924 hypothetical protein. | SMC domain protein; May be involved in recombinational repair of damaged DNA. | 0.695 |
Dde_2974 | Dde_2596 | Dde_2974 | Dde_2596 | PFAM: Peptidase S24/S26A/S26B, conserved region; KEGG: dvl:Dvul_0458 prophage repressor; Belongs to the peptidase S24 family. | SMC domain protein; May be involved in recombinational repair of damaged DNA. | 0.614 |
Dde_2974 | recA | Dde_2974 | Dde_2373 | PFAM: Peptidase S24/S26A/S26B, conserved region; KEGG: dvl:Dvul_0458 prophage repressor; Belongs to the peptidase S24 family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.939 |