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gmk gmk guaA guaA Dde_2720 Dde_2720 Dde_0140 Dde_0140 gpt gpt Dde_2112 Dde_2112 rpoZ rpoZ Dde_1362 Dde_1362 Dde_1032 Dde_1032 ndk ndk Dde_1569 Dde_1569
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (206 aa)    
Predicted Functional Partners:
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
 
 
 0.977
Dde_2720
PFAM: Protein of unknown function DUF370; KEGG: das:Daes_2314 hypothetical protein; Belongs to the RemA family.
  
    0.960
Dde_0140
PFAM: Phosphoribosyltransferase; KEGG: dra:DR_0878 adenine phosphoribosyltransferase.
  
 
 0.956
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
  
 
 0.956
Dde_2112
TIGRFAM: Hypoxanthine phosphoribosyl transferase; KEGG: dvl:Dvul_1545 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
  
 0.947
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
  
 0.939
Dde_1362
KEGG: dvl:Dvul_0821 calcium-binding EF-hand-containing protein.
    
 0.939
Dde_1032
TIGRFAM: Pyruvate kinase; KEGG: dvm:DvMF_0965 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; Belongs to the pyruvate kinase family.
 
 
 0.938
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 0.930
Dde_1569
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.930
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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