STRINGSTRING
ahcY ahcY metE metE Dde_2115 Dde_2115 Dde_2146 Dde_2146 Dde_0276 Dde_0276 Dde_3007 Dde_3007 Dde_3080 Dde_3080 metK metK Dde_2731 Dde_2731 glyA glyA Dde_3135 Dde_3135
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (479 aa)    
Predicted Functional Partners:
metE
5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.976
Dde_2115
Methionine synthase; KEGG: dvm:DvMF_0476 homocysteine S-methyltransferase; PFAM: Homocysteine S-methyltransferase; Dihydropteroate synthase, DHPS; Methionine synthase, cobalamin (vitamin B12)-binding module, cap; Cobalamin (vitamin B12)-binding.
  
 
 0.966
Dde_2146
NIL domain-containing protein; PFAM: NIL domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: dvl:Dvul_1236 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
  
 
  0.917
Dde_0276
Cystathionine beta-lyase; KEGG: dal:Dalk_4468 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.
     
  0.900
Dde_3007
PFAM: Protein of unknown function DUF39; KEGG: dvm:DvMF_1464 protein of unknown function DUF39.
     
  0.900
Dde_3080
TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; KEGG: dvm:DvMF_2658 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.897
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
 
 
 0.890
Dde_2731
PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; KEGG: dvm:DvMF_1412 homoserine dehydrogenase.
   
 
 0.817
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
 0.782
Dde_3135
KEGG: dvm:DvMF_2579 transcriptional regulator, ArsR family; PFAM: Methyltransferase type 11; HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR.
     
 0.781
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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