node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dde_1764 | carB | Dde_1764 | Dde_0333 | KEGG: dvm:DvMF_0434 phosphoribosylformylglycinamidine synthase. | SMART: MGS-like; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG: dvm:DvMF_2306 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Carbamoyl phosphate synthase, large subunit, N-terminal; Belongs to the CarB family. | 0.994 |
Dde_1764 | guaA | Dde_1764 | Dde_1470 | KEGG: dvm:DvMF_0434 phosphoribosylformylglycinamidine synthase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.857 |
Dde_1764 | purC | Dde_1764 | Dde_1007 | KEGG: dvm:DvMF_0434 phosphoribosylformylglycinamidine synthase. | TIGRFAM: SAICAR synthetase; KEGG: dvm:DvMF_2815 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | 0.956 |
Dde_1764 | purD | Dde_1764 | Dde_3458 | KEGG: dvm:DvMF_0434 phosphoribosylformylglycinamidine synthase. | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM: Phosphoribosylglycinamide synthetase; HAMAP: Phosphoribosylglycinamide synthetase; KEGG: dvl:Dvul_2453 phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.994 |
Dde_1764 | purE | Dde_1764 | Dde_3459 | KEGG: dvm:DvMF_0434 phosphoribosylformylglycinamidine synthase. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.983 |
Dde_1764 | purF | Dde_1764 | Dde_0334 | KEGG: dvm:DvMF_0434 phosphoribosylformylglycinamidine synthase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.997 |
Dde_1764 | purL | Dde_1764 | Dde_3191 | KEGG: dvm:DvMF_0434 phosphoribosylformylglycinamidine synthase. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.999 |
Dde_1764 | purM | Dde_1764 | Dde_1672 | KEGG: dvm:DvMF_0434 phosphoribosylformylglycinamidine synthase. | TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: dvl:Dvul_1668 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein. | 0.999 |
Dde_1764 | purN | Dde_1764 | Dde_2835 | KEGG: dvm:DvMF_0434 phosphoribosylformylglycinamidine synthase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.997 |
Dde_1764 | purT | Dde_1764 | Dde_2767 | KEGG: dvm:DvMF_0434 phosphoribosylformylglycinamidine synthase. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.988 |
carB | Dde_1764 | Dde_0333 | Dde_1764 | SMART: MGS-like; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG: dvm:DvMF_2306 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Carbamoyl phosphate synthase, large subunit, N-terminal; Belongs to the CarB family. | KEGG: dvm:DvMF_0434 phosphoribosylformylglycinamidine synthase. | 0.994 |
carB | guaA | Dde_0333 | Dde_1470 | SMART: MGS-like; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG: dvm:DvMF_2306 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Carbamoyl phosphate synthase, large subunit, N-terminal; Belongs to the CarB family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.990 |
carB | purC | Dde_0333 | Dde_1007 | SMART: MGS-like; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG: dvm:DvMF_2306 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Carbamoyl phosphate synthase, large subunit, N-terminal; Belongs to the CarB family. | TIGRFAM: SAICAR synthetase; KEGG: dvm:DvMF_2815 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | 0.951 |
carB | purD | Dde_0333 | Dde_3458 | SMART: MGS-like; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG: dvm:DvMF_2306 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Carbamoyl phosphate synthase, large subunit, N-terminal; Belongs to the CarB family. | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM: Phosphoribosylglycinamide synthetase; HAMAP: Phosphoribosylglycinamide synthetase; KEGG: dvl:Dvul_2453 phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.949 |
carB | purE | Dde_0333 | Dde_3459 | SMART: MGS-like; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG: dvm:DvMF_2306 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Carbamoyl phosphate synthase, large subunit, N-terminal; Belongs to the CarB family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.992 |
carB | purF | Dde_0333 | Dde_0334 | SMART: MGS-like; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG: dvm:DvMF_2306 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Carbamoyl phosphate synthase, large subunit, N-terminal; Belongs to the CarB family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.999 |
carB | purL | Dde_0333 | Dde_3191 | SMART: MGS-like; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG: dvm:DvMF_2306 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Carbamoyl phosphate synthase, large subunit, N-terminal; Belongs to the CarB family. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.947 |
carB | purM | Dde_0333 | Dde_1672 | SMART: MGS-like; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG: dvm:DvMF_2306 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Carbamoyl phosphate synthase, large subunit, N-terminal; Belongs to the CarB family. | TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: dvl:Dvul_1668 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein. | 0.978 |
carB | purN | Dde_0333 | Dde_2835 | SMART: MGS-like; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG: dvm:DvMF_2306 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Carbamoyl phosphate synthase, large subunit, N-terminal; Belongs to the CarB family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.919 |
carB | purT | Dde_0333 | Dde_2767 | SMART: MGS-like; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG: dvm:DvMF_2306 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Carbamoyl phosphate synthase, large subunit, N-terminal; Belongs to the CarB family. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.676 |