node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dde_0398 | Dde_0399 | Dde_0398 | Dde_0399 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: dvl:Dvul_2624 acetolactate synthase catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central region. | PFAM: Amino acid-binding ACT; KEGG: dvu:DVU0361 acetolactate synthase 1 regulatory subunit. | 0.998 |
Dde_0398 | Dde_2167 | Dde_0398 | Dde_2167 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: dvl:Dvul_2624 acetolactate synthase catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central region. | KEGG: dvm:DvMF_0154 acetolactate synthase 3 regulatory subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 0.997 |
Dde_0398 | Dde_2168 | Dde_0398 | Dde_2168 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: dvl:Dvul_2624 acetolactate synthase catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central region. | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: dvm:DvMF_0153 acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central region. | 0.908 |
Dde_0398 | Dde_3130 | Dde_0398 | Dde_3130 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: dvl:Dvul_2624 acetolactate synthase catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central region. | KEGG: dvm:DvMF_2624 acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 0.997 |
Dde_0398 | ilvD | Dde_0398 | Dde_0116 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: dvl:Dvul_2624 acetolactate synthase catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central region. | TIGRFAM: Dihydroxy-acid dehydratase; KEGG: dvu:DVU3373 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.947 |
Dde_0398 | leuA | Dde_0398 | Dde_3218 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: dvl:Dvul_2624 acetolactate synthase catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central region. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.936 |
Dde_0398 | leuB | Dde_0398 | Dde_3222 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: dvl:Dvul_2624 acetolactate synthase catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central region. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.980 |
Dde_0398 | leuC | Dde_0398 | Dde_3219 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: dvl:Dvul_2624 acetolactate synthase catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central region. | Homoaconitate hydratase family protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.766 |
Dde_0398 | leuD | Dde_0398 | Dde_3220 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: dvl:Dvul_2624 acetolactate synthase catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central region. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.806 |
Dde_0398 | sucD | Dde_0398 | Dde_2334 | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: dvl:Dvul_2624 acetolactate synthase catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central region. | Succinyl-CoA synthetase, alpha/beta subunit (sucCD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.584 |
Dde_0399 | Dde_0398 | Dde_0399 | Dde_0398 | PFAM: Amino acid-binding ACT; KEGG: dvu:DVU0361 acetolactate synthase 1 regulatory subunit. | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: dvl:Dvul_2624 acetolactate synthase catalytic subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central region. | 0.998 |
Dde_0399 | Dde_2167 | Dde_0399 | Dde_2167 | PFAM: Amino acid-binding ACT; KEGG: dvu:DVU0361 acetolactate synthase 1 regulatory subunit. | KEGG: dvm:DvMF_0154 acetolactate synthase 3 regulatory subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 0.919 |
Dde_0399 | Dde_2168 | Dde_0399 | Dde_2168 | PFAM: Amino acid-binding ACT; KEGG: dvu:DVU0361 acetolactate synthase 1 regulatory subunit. | TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: dvm:DvMF_0153 acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central region. | 0.992 |
Dde_0399 | Dde_3130 | Dde_0399 | Dde_3130 | PFAM: Amino acid-binding ACT; KEGG: dvu:DVU0361 acetolactate synthase 1 regulatory subunit. | KEGG: dvm:DvMF_2624 acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 0.962 |
Dde_0399 | ilvD | Dde_0399 | Dde_0116 | PFAM: Amino acid-binding ACT; KEGG: dvu:DVU0361 acetolactate synthase 1 regulatory subunit. | TIGRFAM: Dihydroxy-acid dehydratase; KEGG: dvu:DVU3373 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.635 |
Dde_0399 | leuA | Dde_0399 | Dde_3218 | PFAM: Amino acid-binding ACT; KEGG: dvu:DVU0361 acetolactate synthase 1 regulatory subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.906 |
Dde_0399 | leuB | Dde_0399 | Dde_3222 | PFAM: Amino acid-binding ACT; KEGG: dvu:DVU0361 acetolactate synthase 1 regulatory subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.969 |
Dde_0399 | leuC | Dde_0399 | Dde_3219 | PFAM: Amino acid-binding ACT; KEGG: dvu:DVU0361 acetolactate synthase 1 regulatory subunit. | Homoaconitate hydratase family protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.696 |
Dde_0399 | leuD | Dde_0399 | Dde_3220 | PFAM: Amino acid-binding ACT; KEGG: dvu:DVU0361 acetolactate synthase 1 regulatory subunit. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.695 |
Dde_0399 | sucD | Dde_0399 | Dde_2334 | PFAM: Amino acid-binding ACT; KEGG: dvu:DVU0361 acetolactate synthase 1 regulatory subunit. | Succinyl-CoA synthetase, alpha/beta subunit (sucCD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.435 |