node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGE24225.1 | AGE24228.1 | H045_00745 | H045_00760 | Hypothetical protein. | Type IV prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | 0.638 |
AGE24225.1 | AGE24229.1 | H045_00745 | H045_00765 | Hypothetical protein. | Type IV pilus biogenesis protein PilC; COG1459 Type II secretory pathway, component PulF. | 0.638 |
AGE24225.1 | coaE | H045_00745 | H045_00755 | Hypothetical protein. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.638 |
AGE24225.1 | yacG | H045_00745 | H045_00750 | Hypothetical protein. | DNA gyrase inhibitor; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.638 |
AGE24228.1 | AGE24225.1 | H045_00760 | H045_00745 | Type IV prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | Hypothetical protein. | 0.638 |
AGE24228.1 | AGE24229.1 | H045_00760 | H045_00765 | Type IV prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | Type IV pilus biogenesis protein PilC; COG1459 Type II secretory pathway, component PulF. | 0.974 |
AGE24228.1 | coaE | H045_00760 | H045_00755 | Type IV prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.875 |
AGE24228.1 | yacG | H045_00760 | H045_00750 | Type IV prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | DNA gyrase inhibitor; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.800 |
AGE24229.1 | AGE24225.1 | H045_00765 | H045_00745 | Type IV pilus biogenesis protein PilC; COG1459 Type II secretory pathway, component PulF. | Hypothetical protein. | 0.638 |
AGE24229.1 | AGE24228.1 | H045_00765 | H045_00760 | Type IV pilus biogenesis protein PilC; COG1459 Type II secretory pathway, component PulF. | Type IV prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | 0.974 |
AGE24229.1 | coaE | H045_00765 | H045_00755 | Type IV pilus biogenesis protein PilC; COG1459 Type II secretory pathway, component PulF. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.800 |
AGE24229.1 | yacG | H045_00765 | H045_00750 | Type IV pilus biogenesis protein PilC; COG1459 Type II secretory pathway, component PulF. | DNA gyrase inhibitor; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.800 |
AGE26964.1 | coaE | H045_14495 | H045_00755 | Hypothetical protein; COG2091 Phosphopantetheinyl transferase. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.906 |
coaBC | coaD | H045_20220 | H045_19375 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.951 |
coaBC | coaE | H045_20220 | H045_00755 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.625 |
coaBC | mazG | H045_20220 | H045_13435 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Nucleoside triphosphate pyrophosphohydrolase; COG1694 Predicted pyrophosphatase. | 0.913 |
coaD | coaBC | H045_19375 | H045_20220 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.951 |
coaD | coaE | H045_19375 | H045_00755 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.942 |
coaE | AGE24225.1 | H045_00755 | H045_00745 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Hypothetical protein. | 0.638 |
coaE | AGE24228.1 | H045_00755 | H045_00760 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Type IV prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | 0.875 |